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A7641

Sigma-Aldrich

Albumina

lyophilized powder

Sinonimo/i:

Albumina, Ovoalbumina

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About This Item

Numero CAS:
9006-59-1
Numero CE:
232-692-7
Numero MDL:
MFCD00130424
Codice UNSPSC:
12352202
eCl@ss:
42010201
NACRES:
NA.25

Origine biologica

chicken egg white

Tipo

Grade VII

Saggio

≥95% (agarose gel electrophoresis)

Forma fisica

lyophilized powder

PM

44287 Da by calculation

Purificato mediante

chromatography

tecniche

bioconjugation: suitable

N° accesso UniProt

P01012

Temperatura di conservazione

2-8°C

Informazioni sul gene

chicken ... OVAL(396058)

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Descrizione generale

Chicken egg albumin is the major protein constituent of egg whites. Chicken egg albumin is a phosphorylated-glycoprotein. From the amino acid sequence, the peptide portion of the molecule consists of 385 residues and has a molecular weight of 42.7 kDa.
Ovalbumin, an egg white protein is produced in the oviduct of hen. It has 3 sites of post synthetic modification and an N-terminal acetyl group. This product is free of S-ovalbumin, a heat stable form of egg albumin formed when eggs are stored.

Applicazioni

Albumin from chicken egg white has been used:
  • as a component in reaction buffer for in vitro enzymatic assay
  • to simulate dangerous protein toxins
  • as a component in marker solution

The product is useful as a marker (∼45 kDa) for protein electrophoresis. It has been used to produce an animal model of asthma.
Ovalbumin was used as medium for cell incubation in EliCell assay for the detection of released cytokines from eosinophil.
It was also used in a study testing intestinal macromolecule absorption in fetal pig after infusion of colostrum in utero.
Una glicoproteina fosforilata utile come marcatore (circa 45 kDa) per l′elettroforesi delle proteine. È stato usato per produrre un modello animale dell′asma.

Azioni biochim/fisiol

Differential scanning calorimetry indicates that chicken egg albumin denatures at 84 °C. Ovalbumin can be used as a carrier protein to conjugate to synthetic peptides for use as an immunogen.
Ovalbumin is preferred as a nutrient supplement. It can serve as a drug carrier. It possess tumor necrosis releasing factors, that can play a great role in tumor suppression.

Pittogrammi

Health hazard
GHS08

Avvertenze

Danger

Indicazioni di pericolo

H334

Classi di pericolo

Resp. Sens. 1A

Codice della classe di stoccaggio

11 - Combustible Solids

Classe di pericolosità dell'acqua (WGK)

WGK 2

Punto d’infiammabilità (°F)

Not applicable

Punto d’infiammabilità (°C)

Not applicable

Dispositivi di protezione individuale

Eyeshields, Gloves, type N95 (US)

Certificati d'analisi (COA)

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Egg white proteins and their potential use in food processing or as nutraceutical and pharmaceutical agents?A review
Abeyrathne EDNS, et al.
Poultry Science, 92(12), 3292-3299 (2013)
UAF1 is a subunit of multiple deubiquitinating enzyme complexes
Cohn MA, et al.
The Journal of Biological Chemistry, 284(8), 5343-5351 (2009)
Multiplexed immunoassay based on micromotors and microscale tags
Vilela D, et al.
Lab on a chip, 14(18), 3505-3509 (2014)
Intestinal permeability in humans is increased after radiation therapy
Nejdfors P, et al.
Diseases of the Colon and Rectum, 43(11), 1582-1587 (2000)
P T Sangild et al.
Pediatric research, 45(4 Pt 1), 595-602 (1999-04-15)
The ability of the fetal pig intestine to absorb large proteins was investigated in utero. Six pregnant sows were anesthetized (Na pentobarbital) at 99-102 d of gestation (term = 115 +/- 2 d), and a catheter was inserted into the
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Articoli

HPLC Analysis of Protein Standards (1) on BIOshell™ A400 Protein C4

For use as a marker in SDS-PAGE; Albumin from chicken egg white, For use as a marker in SDS-PAGE; L-Lactic Dehydrogenase from rabbit muscle, Type XI, lyophilized powder, 600-1,200 units/mg protein

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