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A4393

R-(−)-Apomorphine hydrochloride hemihydrate

calcined, ≥98% (with NaOH, titration)

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Informazioni su questo articolo

Formula condensata:
C17H17NO2 · HCl · 1/2H2O
Numero CAS:
Peso molecolare:
312.79
NACRES:
NA.77
PubChem Substance ID:
UNSPSC Code:
12352210
EC Number:
206-243-0
MDL number:
Assay:
≥98% (with NaOH, titration)
Form:
calcined, (Powder to Crystalline Powder)
Storage condition:
protect from light, under inert gas
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Quality Segment

assay

≥98% (with NaOH, titration)

form

calcined, (Powder to Crystalline Powder)

storage condition

protect from light, under inert gas

color

white to gray

mp

285-287 °C (lit.)

solubility

H2O: ~10 mg/mL, clear, yellow-green

SMILES string

Cl[H].Cl[H].[H]O[H].[H][C@]12Cc3ccc(O)c(O)c3-c4cccc(CCN1C)c24.[H][C@]56Cc7ccc(O)c(O)c7-c8cccc(CCN5C)c68

InChI

1S/2C17H17NO2.2ClH.H2O/c2*1-18-8-7-10-3-2-4-12-15(10)13(18)9-11-5-6-14(19)17(20)16(11)12;;;/h2*2-6,13,19-20H,7-9H2,1H3;2*1H;1H2/t2*13-;;;/m11.../s1

InChI key

CXWQXGNFZLHLHQ-DPFCLETOSA-N

Gene Information

Application

R-(-)-Apomorphine hydrochloride hemihydrate has been used as a dopamine receptor agonist to study its effects of rotational behavior in rat models of Parkinson′s disease.

Biochem/physiol Actions

R-(−)-Apomorphine acts as a non-selective D1 and D2 dopamine receptor agonist. It shows therapeutic effects against Parkinson′s disease and male erectile dysfunction. R-(−)-Apomorphine also shows neuroprotective, radical scavenging, and emetic effects. Apomorphine stimulates the brain chemoreceptor trigger zone. It stimulates the chemoreceptor trigger zone in the brain.

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Questo articolo
PHR26211041008M003
description

calcined, ≥98% (with NaOH, titration)

description

Pharmaceutical Secondary Standard; Certified Reference Material

description

United States Pharmacopeia (USP) Reference Standard

description

powder, ≥98% (HPLC)

form

calcined, (Powder to Crystalline Powder)

form

solid

form

-

form

powder

assay

≥98% (with NaOH, titration)

assay

-

assay

-

assay

≥98% (HPLC)

Quality Level

200

Quality Level

300

Quality Level

-

Quality Level

100

solubility

H2O: ~10 mg/mL, clear, yellow-green

solubility

-

solubility

-

solubility

H2O: >10 mg/mL

storage condition

protect from light, under inert gas

storage condition

-

storage condition

-

storage condition

-

color

white to gray

color

-

color

-

color

white


Pittogrammi

Skull and crossbones

Parola di avvertenza

Danger

Codici di pericolo

Hazard Classifications

Acute Tox. 3 Oral

Classe di stoccaggio

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

Punto di infiammabilità (°F)

Not applicable

Punto di infiammabilità (°C)

Not applicable

DPI (dispositivi di protezione individuale)

dust mask type N95 (US), Eyeshields, Faceshields, Gloves



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Questions

  1. How many doses in the 100mg bottle?

    1 answer
    1. This product is a research grade chemical and not a pharmaceutical product. While the same active enantiomer (R-(−)-apomorphine) is an approved medicine, it is not manufactured, packaged, or regulated as a clinical dosage form, so it should not be used in humans.

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