94742

Vanadyl ribonucleoside complexes solution

BioReagent, for molecular biology, 200 mM

• Sinonimo/i: Ribonucleoside vanadyl complexes
• Codice UNSPSC: 12352200
• NACRES: NA.52

Proprietà

• Grado: Molecular Biology; for molecular biology
• Nome Commerciale: BioReagent
• Stato: liquid
• Concentrazione: 200 mM
• Impurezze: oxovanadium V
• Compatibilità: in accordance for ribonuclease inhibition test
• Condizioni di spedizione: dry ice
• Temperatura di conservazione: −20°C

Descrizione

Descrizione generale

Vanadyl ribonucleoside complexes are low molecular weight inhibitors of ribonucleases.[1]

Vanadyl ribonucleoside complexes solution is an inhibitor for ribonuclease (RNase).[2] Use of vanadyl ribonucleoside complexes exhibits protection from degradation by RNase in tissue, genomic, RNA and protein samples.[3]

Applicazioni

Vanadyl ribonucleoside complexes (VDR) are transition state analogs that bind to active sites of many RNases, inhibiting their activity. Because the RNases are not covalently modified by the complexes, VDR must be used at every stage of RNA extraction and purification. However, VDR also inhibit RNA polymerases and in vitro translation and therefore must be removed from final preparation of RNA.

Vanadyl ribonucleoside complexes solution has been used:

• as a component of polysome lysis buffer[4] and fluorescence in situ hybridization (FISH) buffer[5][6]
• as a RNase inhibitor for the isolation of endogenous YTH domain-containing 2 protein (YTHDC2) from mouse testes[7]

Informazioni sulla sicurezza

• Codice della classe di stoccaggio: 10 - Combustible liquids
• Classe di pericolosità dell'acqua (WGK): WGK 3
• Punto d’infiammabilità (°F): Not applicable
• Punto d’infiammabilità (°C): Not applicable