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93422

Triton^™ X-114

Name: Triton<SUP>™</SUP> X-114
Brand: SIGMA

Sinonimo/i:

(1,1,3,3-Tetramethylbutyl)phenyl-polyethylene glycol, Polyethylene glycol tert-octylphenyl ether

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Informazioni su questo articolo

Formula condensata:

(C₂H₄O)n C₁₄H₂₂O, n = 7 or 8

Numero CAS:

9036-19-5

UNSPSC Code:

12161900

NACRES:

NA.21

PubChem Substance ID:

57653556

MDL number:

MFCD00128254

Beilstein/REAXYS Number:

2315025

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Proprietà

description

non-ionic

Quality Segment

200

form

liquid

mol wt

average mol wt 537

impurities

≤0.001% peroxides (as H₂O₂), ≤1% water

ign. residue

≤0.2%

refractive index

n20/D 1.488 (lit.), n20/D 1.495

CMC

0.2 mM (20-25°C)

transition temp

pour point ~−9 °C, cloud point 23 °C

anion traces

chloride (Cl^-): ≤50 mg/kg, sulfate (SO₄^2-): ≤50 mg/kg

cation traces

Ca: ≤10 mg/kg, Cd: ≤5 mg/kg, Co: ≤5 mg/kg, Cr: ≤5 mg/kg, Cu: ≤5 mg/kg, Fe: ≤15 mg/kg, K: ≤500 mg/kg, Mg: ≤5 mg/kg, Mn: ≤5 mg/kg, Na: ≤500 mg/kg, Ni: ≤5 mg/kg, Pb: ≤5 mg/kg, Zn: ≤5 mg/kg

HLB

12.4

SMILES string

CC(C)(C)CC(C)(C)c1ccc(OCCOCCOCCOCCOCCOCCOCCO)cc1

InChI

1S/C28H50O8/c1-27(2,3)24-28(4,5)25-6-8-26(9-7-25)36-23-22-35-21-20-34-19-18-33-17-16-32-15-14-31-13-12-30-11-10-29/h6-9,29H,10-24H2,1-5H3

InChI key

HNLXNOZHXNSSPN-UHFFFAOYSA-N

Descrizione

General description

Triton^™ X-114 is a nonionic detergent. It is a good detergent for solubilizing membranes having reversible phase-separation property useful for the separation of intrinsic membrane proteins.[1] Solution of Triton^™ X-114 is homogeneous at 0°C but phase separation into aqueous phase and a detergent phase occurs above 20°C.[2] Phase separation of proteins in solutions of Triton^™ X-114 has been investigated.[2] This octylphenol ethoxylate is compatible with anionic, cationic, and other nonionic surfactants and chemically stable in most acidic & alkaline solutions.

Application

Triton^™ X-114 has been used:

In phase separation of integral membrane proteins[3]
In the purification of bacterial inclusion bodies
To study the clouding phenomenon in promethazine hydrochloride, an amphiphilic phenothiazine drug
To partition conditioned media into insoluble and soluble phases before Western blotting[4]
For solubilization of phosphatidylinositol 4-phosphate 5-kinase from bovine brain

Legal Information

Triton is a trademark of The Dow Chemical Company or an affiliated company of Dow

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Questo articolo	X114	X100	T9284
Sigma-Aldrich 93422 Triton^™ X-114	Sigma-Aldrich X114 Triton^™ X-114	Sigma-Aldrich X100 Triton^™ X-100	Sigma-Aldrich T9284 Triton^™ X-100
form liquid	form -	form liquid	form liquid
cation traces Ca: ≤10 mg/kg, Co: ≤5 mg/kg, Cu: ≤5 mg/kg, K: ≤500 mg/kg, Mn: ≤5 mg/kg, Ni: ≤5 mg/kg, Zn: ≤5 mg/kg, Cd: ≤5 mg/kg, Fe: ≤15 mg/kg, Na: ≤500 mg/kg, Cr: ≤5 mg/kg, Pb: ≤5 mg/kg, Mg: ≤5 mg/kg	cation traces -	cation traces -	cation traces Al: ≤0.0005%, Ca: ≤0.0005%, Cu: ≤0.0005%, Fe: ≤0.0005%, K: ≤0.005%, Mg: ≤0.0005%, NH₄⁺: ≤0.05%, Na: ≤0.1%, Pb: ≤0.001%, Zn: ≤0.0005%
description non-ionic	description non-ionic	description non-ionic	description non-ionic
anion traces chloride (Cl^-): ≤50 mg/kg, sulfate (SO₄^2-): ≤50 mg/kg	anion traces -	anion traces -	anion traces chloride (Cl^-): ≤0.05%, sulfate (SO₄^2-): ≤0.05%
CMC 0.2 mM (20-25°C)	CMC 0.2 mM (20-25°C)	CMC 0.2-0.9 mM (20-25°C)	CMC 0.2-0.9 mM (20-25°C)
mol wt average mol wt 537	mol wt average mol wt 537	mol wt micellar avg mol wt 80,000, average mol wt 625	mol wt micellar avg mol wt 80,000, average mol wt 625

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pictograms

GHS05,GHS07,GHS09

signalword

Danger

Classe di stoccaggio

10 - Combustible liquids

wgk

WGK 3

flash_point_f

483.8 °F - closed cup

flash_point_c

251 °C - closed cup

ppe

Eyeshields, Gloves, type ABEK (EN14387) respirator filter

hcodes

H302,H315,H318,H410,EUH430

pcodes

P201 - P202 - P273 - P280 - P305 + P351 + P338 - P391 - P405 - P501

Hazard Classifications

Acute Tox. 4 Oral - Aquatic Acute 1 - Aquatic Chronic 1 - ED ENV 1 - Eye Dam. 1 - Skin Irrit. 2

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