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Merck
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37970

Sigma-Aldrich

5,7-Dihydroxytryptamine creatinine sulfate salt

≥97.0% (HPLC)

Sinonimo/i:

5,7-DHT, 7-Hydroxyserotonin creatinine sulfate salt

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About This Item

Formula empirica (notazione di Hill):
C10H12N2O2 · C4H7N3O · H2SO4
Numero CAS:
Peso molecolare:
403.41
Beilstein:
8817524
Numero MDL:
Codice UNSPSC:
12352200
ID PubChem:

Saggio

≥97.0% (HPLC)

Condizioni di spedizione

wet ice

Temperatura di conservazione

−20°C

Stringa SMILE

OS(O)(=O)=O.CN1CC(=O)N=C1N.NCCc2c[nH]c3c(O)cc(O)cc23

InChI

1S/C10H12N2O2.C4H7N3O.H2O4S/c11-2-1-6-5-12-10-8(6)3-7(13)4-9(10)14;1-7-2-3(8)6-4(7)5;1-5(2,3)4/h3-5,12-14H,1-2,11H2;2H2,1H3,(H2,5,6,8);(H2,1,2,3,4)
BXYXUOWJXUUTQZ-UHFFFAOYSA-N

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Azioni biochim/fisiol

Neurotoxin that is relatively selective for serotonergic terminals in adults and gives long-lasting destruction of serotonergic neurons when given neonatally; adrenergic neurotoxicity can be blocked by pretreating with desipramine.

Pittogrammi

Exclamation mark

Avvertenze

Warning

Indicazioni di pericolo

Classi di pericolo

Acute Tox. 4 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral

Codice della classe di stoccaggio

11 - Combustible Solids

Classe di pericolosità dell'acqua (WGK)

WGK 3

Punto d’infiammabilità (°F)

Not applicable

Punto d’infiammabilità (°C)

Not applicable

Dispositivi di protezione individuale

dust mask type N95 (US), Eyeshields, Gloves


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Tatsunori Tanaka et al.
The international journal of neuropsychopharmacology, 20(5), 410-421 (2016-12-31)
Isolation-reared mice show social encounter-induced hyperactivity with activation of prefrontal serotonergic and dopaminergic systems, but it is not known whether this stress response is observed in other pathological conditions. Here we examined whether the social encounter stimulation induces abnormal behavior
Lining Cao et al.
Frontiers in cellular neuroscience, 11, 131-131 (2017-05-24)
In the brain, the serotonergic neurons located in the raphe nucleus are the unique resource of the neurotransmitter serotonin, which plays a pivotal role in the regulation of brain development and functions. Dysfunction of the serotonin system is present in
Victoria M Smith et al.
The European journal of neuroscience, 42(10), 2805-2817 (2015-10-13)
Light serves as the primary stimulus that synchronizes the circadian clock in the suprachiasmatic nucleus (SCN) to the external day/night cycle. Appropriately timed light exposure can reset the phase of the circadian clock. Some serotonergic drugs that bind to the
Hai Lin et al.
Neuroscience letters, 598, 91-95 (2015-05-20)
Although tianeptine, an atypical antidepressant has been reported to have antinociceptive effects, the mode of action is different from that of tricyclic antidepressants despite structural similarities. We examined the antiallodynic effect of intrathecal tianeptine in neuropathic pain rats and determined
P Campus et al.
Psychopharmacology, 233(7), 1157-1169 (2016-01-06)
The expression of sign-tracking (ST) phenotype over goal-tracking (GT) phenotype has been associated to different aspects of impulsive behavior, and depletions of brain serotonin (5-HT) have been shown to selectively increase impulsive action as well as ST. The present study

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