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16702

Sigma-Aldrich

(R)-Pantetheine

≥95.0% (HPLC)

Sinonimo/i:

(2R)-2,4-Dihydroxy-N-[3-[(2-mercaptoethyl)amino]-3-oxopropyl]-3,3-dimethylbutanamide, (R)-2,4-Dihydroxy-N-[2-[(2-mercaptoethyl)carbamoyl]ethyl]-3,3-dimethylbutyramide, (D)-(+)-Pantetheine, N-(Pantothenyl)-β-aminoethanethiol, LBF, Lactobacillus bulgaricus factor

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About This Item

Formula empirica (notazione di Hill):
C11H22N2O4S
Numero CAS:
496-65-1
Peso molecolare:
278.37
Beilstein:
1714196
Numero MDL:
MFCD00056757
Codice UNSPSC:
12352205
ID PubChem:
329751343
NACRES:
NA.79
Prezzi e disponibilità al momento non sono disponibili

Saggio

≥95.0% (HPLC)

Stato

solid

Attività ottica

[α]/D 17±2°, c = 1 in H2O

Colore

white

Temperatura di conservazione

−20°C

Stringa SMILE

OCC(C)(C)[C@@H](O)C(NCCC(NCCS)=O)=O

InChI

1S/C11H22N2O4S/c1-11(2,7-14)9(16)10(17)13-4-3-8(15)12-5-6-18/h9,14,16,18H,3-7H2,1-2H3,(H,12,15)(H,13,17)/t9-/m0/s1
ZNXZGRMVNNHPCA-VIFPVBQESA-N

Applicazioni


  • Structures of carboxylic acid reductase reveal domain dynamics underlying catalysis: This study investigates the structural and dynamic aspects of carboxylic acid reductase enzymes, which are relevant for the conversion processes involving (R)-pantetheine and related compounds (Gahloth et al., 2017).

Azioni biochim/fisiol

Metabolite in carbapenem biosynthesis, pantothenate and CoA biosynthesis and biosynthesis of secondary metabolites.

Codice della classe di stoccaggio

11 - Combustible Solids

Classe di pericolosità dell'acqua (WGK)

WGK 3

Punto d’infiammabilità (°F)

Not applicable

Punto d’infiammabilità (°C)

Not applicable

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Certificati d'analisi (COA)

Lot/Batch Number
BCCB7634
BCBZ9006
BCBM8211V
BCBM8211

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H Kleinkauf et al.
Proceedings of the National Academy of Sciences of the United States of America, 68(9), 2069-2072 (1971-09-01)
To study the function of pantetheine in gramicidin S and tyrocidine biosynthesis, pepsin digests of the polymerizing enzymes, of which only the heavy ones contain pantetheine, were analyzed. The digests of gramicidin S enzymes charged with either [(14)C]proline or with
C T Wittwer et al.
The Journal of biological chemistry, 258(16), 9733-9738 (1983-08-25)
A microsomal glycoprotein that catalyzes the hydrolysis of pantetheine to pantothenate and cysteamine was solubilized and purified to homogeneity as determined by sodium dodecyl sulfate electrophoresis. The enzyme from pig kidney cortex was solubilized on exposure to butanol and purified
Jun Yang et al.
Applied optics, 57(10), 2490-2498 (2018-05-02)
On-site measurements and defect detection are of great importance for precision ground steel rollers due to their large dimension and weight. In addition to dimensional error, form accuracy, surface roughness, and surface/sub-surface cracks, there also exist optical defect requirements for
Patrice Brassard et al.
Critical care medicine, 44(4), 755-763 (2015-11-21)
Sympathetic vasoconstriction regulates peripheral circulation and controls blood pressure, but sepsis is associated with hypotension. We evaluated whether apparent loss of sympathetic vasoconstrictor responsiveness relates to distended smooth muscles or to endotoxemia and/or hypoxia. Prospective descriptive study. Hospital research laboratory.
Laura B Ferguson et al.
Molecular neurobiology, 56(4), 2791-2810 (2018-08-01)
Alcohol use disorder (AUD) is a complex psychiatric disorder with strong genetic and environmental risk factors. We studied the molecular perturbations underlying risky drinking behavior by measuring transcriptome changes across the neurocircuitry of addiction in a genetic mouse model of
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