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130M-9

Sigma-Aldrich

CD30 (Ber-H2) Mouse Monoclonal Antibody

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About This Item

Codice UNSPSC:
12352203
NACRES:
NA.41

Origine biologica

mouse

Livello qualitativo

100
500

Coniugato

unconjugated

Forma dell’anticorpo

culture supernatant

Tipo di anticorpo

primary antibodies

Clone

Ber-H2, monoclonal

Descrizione

For In Vitro Diagnostic Use in Select Regions (See Chart)

Forma fisica

buffered aqueous solution

Reattività contro le specie

human

Confezionamento

vial of 0.1 mL concentrate (130M-94)
vial of 0.5 mL concentrate (130M-95)
bottle of 1.0 mL predilute (130M-97)
vial of 1.0 mL concentrate (130M-96)
bottle of 7.0 mL predilute (130M-98)

Produttore/marchio commerciale

Cell Marque™

tecniche

immunohistochemistry (formalin-fixed, paraffin-embedded sections): 1:50-1:200

Isotipo

IgG1κ

Controllo

classic Hodgkin lymphoma

Condizioni di spedizione

wet ice

Temperatura di conservazione

2-8°C

Visualizzazione

membranous

Informazioni sul gene

human ... TNFRSF8(943)

Categorie correlate

Descrizione generale

Anti-CD30 detects a formalin-resistant epitope that is expressed by Reed-Sternberg cells in classic Hodgkin lymphoma, the majority of anaplastic large cell lymphomas, primary cutaneous CD30 positive T-cell lymphoproliferative disorders, and in embryonal carcinomas. Occasionally diffuse large B-cell lymphoma stains with this antibody. This antibody also stains plasma cells in paraffin-embedded tissue. However, reactive immunoblasts are immunoreactive with this antibody. The staining pattern of anti-CD30 in lymphoma or embryonal carcinoma is different, with the former being membranous and exhibiting Golgi zone accentuation in location, and the latter being membranous only.

Qualità


IVD
IVD
IVD
RUO

Linkage

CD30 Positive Control Slides, Product No. 130S, are available for immunohistochemistry (formalin-fixed, paraffin-embedded sections).

Stato fisico

Solution in Tris Buffer, pH 7.3-7.7, with 1% BSA and <0.1% Sodium Azide

Nota sulla preparazione

Download the IFU specific to your product lot and formatNote: This requires a keycode which can be found on your packaging or product label.

Altre note

For Technical Service please contact: 800-665-7284 or email: service@cellmarque.com

Note legali

Cell Marque is a trademark of Merck KGaA, Darmstadt, Germany

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Certificati d'analisi (COA)

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R Schwarting et al.
Blood, 74(5), 1678-1689 (1989-10-01)
The production and characterization of a monoclonal antibody (MoAb) designated Ber-H2, directed against a new epitope of the Ki-1 (CD30) antigen, are described. In comparison with the formerly reported Ki-1 MoAb whose reactivity with Hodgkin and Reed-Sternberg (H-RS) cells in
David H George et al.
The American journal of surgical pathology, 27(4), 487-493 (2003-03-27)
Anaplastic large cell lymphoma (ALCL) rarely occurs in the central nervous system. Although defined by its composition of large, pleomorphic, CD30-positive lymphocytes, ALCL is heterogeneous. Most are T cell but some are null cell. Most but not all have a
Rabban JT, et al.
Diagnostic Immunohistochemistry: Theranostic and Genomic Applications, 702-702 (2014)
Cyrus V Hedvat et al.
Human pathology, 33(10), 968-974 (2002-10-24)
The immunohistochemical analysis of lymphoid neoplasms has led to refined classification schemes based on the profile of antigen expression and correlation with morphological, cytogenetic, molecular, and clinical features. Tissue microarrays (TMAs) are a powerful tool to rapidly characterize the phenotypic

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