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118R-1

Sigma-Aldrich

CD38 (SP149) Rabbit Monoclonal Antibody

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About This Item

Codice UNSPSC:
12352203
NACRES:
NA.41

Origine biologica

rabbit

Livello qualitativo

100
500

Coniugato

unconjugated

Forma dell’anticorpo

culture supernatant

Tipo di anticorpo

primary antibodies

Clone

SP149, monoclonal

Descrizione

For In Vitro Diagnostic Use in Select Regions (See Chart)

Forma fisica

buffered aqueous solution

Reattività contro le specie

human

Confezionamento

vial of 0.1 mL concentrate (118R-14)
vial of 0.5 mL concentrate (118R-15)
bottle of 1.0 mL predilute (118R-17)
vial of 1.0 mL concentrate (118R-16)
bottle of 7.0 mL predilute (118R-18)

Produttore/marchio commerciale

Cell Marque™

tecniche

immunohistochemistry (formalin-fixed, paraffin-embedded sections): 1:100-1:500

Isotipo

IgG

Controllo

bone marrow, lymph node, plasma cell myeloma

Condizioni di spedizione

wet ice

Temperatura di conservazione

2-8°C

Visualizzazione

cytoplasmic

Informazioni sul gene

human ... CD38(952)

Categorie correlate

Descrizione generale

CD38 molecule is a 46-kDa type-II transmembrane glycoprotein with a short N-terminalcytoplasmic tail (20 amino acids) and a long extracellular domain (256 amino acids). Itis present on many hematopoietic cells, especially plasma cells, and in some solid tumortissues. CD38 is one of the early expressed markers of mature naive B-cell activation and it isuseful in identifying functional mature B-lymphocyte subsets.

Qualità


IVD
IVD
IVD
RUO

Linkage

CD38 Positive Control Slides, Product No. 118S, are available for immunohistochemistry (formalin-fixed, paraffin-embedded sections).

Stato fisico

Solution in Tris Buffer, pH 7.3-7.7, with 1% BSA and <0.1% Sodium Azide

Nota sulla preparazione

Download the IFU specific to your product lot and formatNote: This requires a keycode which can be found on your packaging or product label.

Altre note

For Technical Service please contact: 800-665-7284 or email: service@cellmarque.com

Note legali

Cell Marque is a trademark of Merck KGaA, Darmstadt, Germany

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Certificati d'analisi (COA)

Cerca il Certificati d'analisi (COA) digitando il numero di lotto/batch corrispondente. I numeri di lotto o di batch sono stampati sull'etichetta dei prodotti dopo la parola ‘Lotto’ o ‘Batch’.

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Flavius Martin et al.
Nature reviews. Immunology, 2(5), 323-335 (2002-05-30)
Recent advances in genomics and proteomics, combined with the facilitated generation and analysis of transgenic and gene-knockout animals, have revealed new complexities in classical biological systems, including the B-cell compartment. Studies on an 'old', but poorly characterized, B-cell subset--the naive
Leoncini, L et al. Burkitt lymphoma. In Swerdlow SH, et al. eds. WHO Classification of Tumours of Haematopoietic and Lymphoid Tissues. IARC, WHO Press, Lyon, France, 2008; 262-264.
Leoncini, L
WHO Classification of Tumours of Haematopoietic and Lymphoid Tissue, 262-264 (2008)
Kikkeri N Naresh et al.
British journal of haematology, 154(6), 770-776 (2011-07-02)
Distinguishing Burkitt lymphoma (BL) from B cell lymphoma, unclassifiable with features intermediate between diffuse large B-cell lymphoma (DLBCL) and BL (DLBCL/BL), and DLBCL is challenging. We propose an immunohistochemistry and fluorescent in situ hybridization (FISH) based scoring system that is
Fabio Malavasi et al.
Physiological reviews, 88(3), 841-886 (2008-07-16)
The membrane proteins CD38 and CD157 belong to an evolutionarily conserved family of enzymes that play crucial roles in human physiology. Expressed in distinct patterns in most tissues, CD38 (and CD157) cleaves NAD(+) and NADP(+), generating cyclic ADP ribose (cADPR)
Sandeep S Dave et al.
The New England journal of medicine, 354(23), 2431-2442 (2006-06-09)
The distinction between Burkitt's lymphoma and diffuse large-B-cell lymphoma is crucial because these two types of lymphoma require different treatments. We examined whether gene-expression profiling could reliably distinguish Burkitt's lymphoma from diffuse large-B-cell lymphoma. Tumor-biopsy specimens from 303 patients with
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