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Y0001183

Trolamine impurity B

European Pharmacopoeia (EP) Reference Standard

Sinonimo/i:

Diethanolamine, 2,2′-Iminodiethanol, Bis(2-hydroxyethyl)amine

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About This Item

Formula condensata:
HN(CH2CH2OH)2
Numero CAS:
111-42-2
Peso molecolare:
105.14
Beilstein:
605315
Numero MDL:
MFCD00002843
Codice UNSPSC:
41116107
ID PubChem:
329831296
NACRES:
NA.24

Grado

pharmaceutical primary standard

Densità del vapore

3.6 (vs air)

Tensione di vapore

<0.98 atm ( 100 °C)

Famiglia di API

trolamine

Temp. autoaccensione

689 °F

Limite di esplosione

10.6 %

Produttore/marchio commerciale

EDQM

Indice di rifrazione

n20/D 1.477 (lit.)

P. ebollizione

217 °C/150 mmHg (lit.)

Punto di fusione

28 °C (lit.)

Densità

1.097 g/mL at 25 °C (lit.)

applicazioni

pharmaceutical (small molecule)

Formato

neat

Temperatura di conservazione

2-8°C

Stringa SMILE

OCCNCCO

InChI

1S/C4H11NO2/c6-3-1-5-2-4-7/h5-7H,1-4H2
ZBCBWPMODOFKDW-UHFFFAOYSA-N

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Categorie correlate

Descrizione generale

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.
For further information and support please go to the website of the issuing Pharmacopoeia.

Applicazioni

Trolamine impurity B EP Reference standard, intended for use in laboratory tests only as specifically prescribed in the European Pharmacopoeia.

Confezionamento

The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity, please visit the EDQM reference substance catalogue.

Altre note

Sales restrictions may apply.

Avvertenze

Danger

Indicazioni di pericolo

H302,H315,H318,H361fd,H373

Classi di pericolo

Acute Tox. 4 Oral - Eye Dam. 1 - Repr. 2 - Skin Irrit. 2 - STOT RE 2 Oral

Organi bersaglio

Kidney,Liver,Blood

Codice della classe di stoccaggio

10 - Combustible liquids

Classe di pericolosità dell'acqua (WGK)

WGK 2

Punto d’infiammabilità (°F)

280.4 °F - closed cup

Punto d’infiammabilità (°C)

138 °C - closed cup

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Certificati d'analisi (COA)

Lot/Batch Number

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Hon-Wing Leung et al.
Regulatory toxicology and pharmacology : RTP, 43(3), 260-271 (2005-09-29)
Diethanolamine (DEA) is a chemical used widely in a number of industries and is present in many consumer products. Studies by the National Toxicology Program (NTP) have indicated that lifetime dermal exposure to DEA increased the incidence and multiplicity of
Choline deficiency associated with diethanolamine carcinogenicity.
Paul M Newberne
Toxicological sciences : an official journal of the Society of Toxicology, 67(1), 1-3 (2002-04-19)
Hae-Rim Kim et al.
PloS one, 10(4), e0124909-e0124909 (2015-04-22)
Vascular endothelial growth factor (VEGF) has angiogenic, inflammatory, and bone-destructive roles in rheumatoid arthritis (RA). We aimed to determine the unique role of VEGF in osteoclastogenesis in RA. VEGF-induced receptor activator of nuclear factor ҡB ligand (RANKL) expression was determined
Honghui Yu et al.
Journal of immunology (Baltimore, Md. : 1950), 193(6), 2902-2910 (2014-08-15)
Anti-D can prevent immunization to the RhD Ag on RBCs, a phenomenon commonly termed Ab-mediated immune suppression (AMIS). The most accepted theory to explain this effect has been the rapid clearance of RBCs. In mouse models using SRBC, these xenogeneic
Xiao-yu Jia et al.
PloS one, 10(4), e0123277-e0123277 (2015-04-16)
The autoantigen of anti-glomerular basement membrane (GBM) disease has been identified as the non-collagenous domain 1 of α3 chain of type IV collagen, α3(IV)NC1. Our previous study revealed a peptide on α3(IV)NC1 as a major linear epitope for B cells
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