1066009

Betamethasone

United States Pharmacopeia (USP) Reference Standard

• Sinonimo/i: 9α-Fluoro-11β,17α,21-trihydroxy-16β-methylpregna-1,4-diene-3,20-dione, 9α-Fluoro-16β-methyl-11β,17α,21-trihydroxy-1,4-pregnadiene-3,20-dione, 9α-Fluoro-16β-methylprednisolone
• Formula empirica (notazione di Hill): C₂₂H₂₉FO₅
• Numero CAS: 378-44-9
• Peso molecolare: 392.46
• NACRES: NA.24
• PubChem Substance ID: 329748930
• UNSPSC Code: 41116107
• MDL number: MFCD00062969

Proprietà

• biological source: synthetic
• grade: pharmaceutical primary standard
• agency: USP
• vapor pressure: <0.0000001 kPa ( 25 °C)
• API family: betamethasone
• packaging: pkg of 200 mg
• manufacturer/tradename: USP
• color: white to off-white
• mp: 235-237 °C (lit.), 447.8-473 °F (231—245°C; decomposes)
• solubility: acetone: sparingly soluble, chloroform: very slightly soluble, ethanol: sparingly soluble, ether: very slightly soluble, methanol: sparingly soluble, water: insoluble
• density: 0.305 g/cm³ at 25 °C (77°F)
• application(s): pharmaceutical; pharmaceutical (small molecule)
• format: neat
• storage temp.: 2-8°C
• SMILES string: [H][C@@]12C[C@H](C)[C@](O)(C(=O)CO)[C@@]1(C)C[C@H](O)[C@@]3(F)[C@@]2([H])CCC4=CC(=O)C=C[C@]34C
• InChI: 1S/C22H29FO5/c1-12-8-16-15-5-4-13-9-14(25)6-7-19(13,2)21(15,23)17(26)10-20(16,3)22(12,28)18(27)11-24/h6-7,9,12,15-17,24,26,28H,4-5,8,10-11H2,1-3H3/t12-,15-,16-,17-,19-,20-,21-,22-/m0/s1
• InChI key: UREBDLICKHMUKA-DVTGEIKXSA-N
• Gene Information: human ... NR3C1(2908)

Descrizione

General description

Find answers to frequently asked questions on USP products in USP FAQs.

Betamethasone, a synthetic glucocorticoid, belongs to the corticosteroid family of active pharmaceutical ingredients (APIs).
This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia.

Application

Betamethasone USP reference standard, intended for use in specified quality tests and assays as specified in the USP compendia. Also, for use with USP monographs such as:

• Betamethasone Acetate
• Betamethasone Oral Solution
• Betamethasone Valerate Cream
• Betamethasone Valerate Lotion
• Betamethasone Valerate Ointment
• Dexamethasone

Analysis Note

These products are for test and assay use only. They are not meant for administration to humans or animals and cannot be used to diagnose, treat, or cure diseases of any kind.  ​

Other Notes

Sales restrictions may apply.

Informazioni sulla sicurezza

• Pittogrammi: GHS08
• Parola di avvertenza: Danger
• Codici di pericolo: H360FD,H373
• Avvertenze di sicurezza: P202 - P260 - P280 - P308 + P313 - P405 - P501
• Hazard Classifications: Repr. 1B - STOT RE 2
• Organi bersaglio: Liver,Kidney,Endocrine system
• Classe di stoccaggio: 6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
• Che succede?: WGK 2
• Punto di infiammabilità (°F): Not applicable
• Punto di infiammabilità (°C): Not applicable