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Merck
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Documenti fondamentali

T8275

Supelco

Temazepam

analytical standard

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About This Item

Formula empirica (notazione di Hill):
C16H13ClN2O2
Numero CAS:
Peso molecolare:
300.74
Numero CE:
Numero MDL:
Codice UNSPSC:
41116107
ID PubChem:
NACRES:
NA.24
Prezzi e disponibilità al momento non sono disponibili

Grado

analytical standard

Livello qualitativo

Controllo stupefacenti

USDEA Schedule IV; Home Office Schedule 3; psychotrope (France); kontrollierte Droge in Deutschland; regulated under CDSA - not available from Sigma-Aldrich Canada; psicótropo (Spain); Decreto Lei 15/93: Tabela IV (Portugal)

tecniche

HPLC: suitable
gas chromatography (GC): suitable

applicazioni

forensics and toxicology
pharmaceutical (small molecule)
veterinary

Formato

neat

Stringa SMILE

CN1C(=O)C(O)N=C(c2ccccc2)c3cc(Cl)ccc13

InChI

1S/C16H13ClN2O2/c1-19-13-8-7-11(17)9-12(13)14(18-15(20)16(19)21)10-5-3-2-4-6-10/h2-9,15,20H,1H3
SEQDDYPDSLOBDC-UHFFFAOYSA-N

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Applicazioni

Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

Azioni biochim/fisiol

Hypnotic

Pittogrammi

Exclamation mark

Avvertenze

Warning

Indicazioni di pericolo

Classi di pericolo

Acute Tox. 4 Oral - STOT SE 3

Organi bersaglio

Central nervous system

Codice della classe di stoccaggio

11 - Combustible Solids

Classe di pericolosità dell'acqua (WGK)

WGK 3

Punto d’infiammabilità (°F)

Not applicable

Punto d’infiammabilità (°C)

Not applicable

Dispositivi di protezione individuale

dust mask type N95 (US), Eyeshields, Gloves


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Certificati d'analisi (COA)

Lot/Batch Number

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Gerben Stege et al.
Respiratory medicine, 104(4), 518-524 (2009-11-17)
Benzodiazepines can improve sleep quality, but are also thought to cause respiratory depression in patients with chronic obstructive pulmonary disease (COPD). The aims of this study were to assess the effects of temazepam on indices of circadian respiratory function, dyspnea
Thomas I F H Cremers et al.
The international journal of neuropsychopharmacology, 13(6), 807-811 (2010-01-06)
Selective serotonin (5-HT) reuptake inhibitors (SSRIs) are used as a first-line treatment in depression. However, many depressed patients are also treated with benzodiazepines to alleviate increased anxiety and sleep disturbances normally associated with depression. Since benzodiazepines inhibit 5-HT neuronal firing
R H Medema et al.
Oncogene, 31(21), 2601-2613 (2011-10-04)
DNA-damaging therapies represent the most frequently used non-surgical anticancer strategies in the treatment of human tumors. These therapies can kill tumor cells, but at the same time they can be particularly damaging and mutagenic to healthy tissues. The efficacy of
David Wang et al.
Journal of sleep research, 20(4), 526-532 (2011-06-15)
Centrally active agents have a variable impact in patients with obstructive sleep apnoea (OSA) that is unexplained. How to phenotype the individual OSA response is clinically important, as it may help to identify who will be at risk of respiratory
Temazepam: pharmacological profile of a benzodiazepine and new trends in its clinical application.
F Fraschini et al.
Pharmacological research, 27(2), 97-113 (1993-02-01)

Questions

1–2 of 2 Questions  
  1. Is Product T8275, Temazepam, soluble in any solvents other than chloroform?  How long can I keep the stock solution?

    1 answer
    1. Product T8275, Temazepam, is soluble in methanol at 1 mg/mL. Tenfold more dilute solutions (0.1 mg/mL) of temazepam in methanol can be stored in glass vials at -20°C for 1 month. Reference: https://www.sciencedirect.com/science/article/pii/S1570023205006331

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  2. What is the Department of Transportation shipping information for this product?

    1 answer
    1. Transportation information can be found in Section 14 of the product's (M)SDS.To access the shipping information for this material, use the link on the product detail page for the product.

      Helpful?

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