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PHR1677

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Anthralin (Dithranol)

Pharmaceutical Secondary Standard; Certified Reference Material

Sinonimo/i:

Dithranol, 1,8,9-Anthracenetriol, 1,8-Dihydroxy-9(10H)-anthracenone, 1,8-Dihydroxyanthrone, Anthralin

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About This Item

Formula empirica (notazione di Hill):
C14H10O3
Numero CAS:
Peso molecolare:
226.23
Beilstein:
2054360
Numero CE:
Numero MDL:
Codice UNSPSC:
41116107
ID PubChem:
NACRES:
NA.24

Grado

certified reference material
pharmaceutical secondary standard

Livello qualitativo

agenzia

traceable to Ph. Eur. D2953000
traceable to USP 1039006

Famiglia di API

anthralin, dithranol

CdA

current certificate can be downloaded

Confezionamento

pkg of 1 g

tecniche

HPLC: suitable
gas chromatography (GC): suitable

Punto di fusione

178-181 °C (lit.)

applicazioni

pharmaceutical (small molecule)

Formato

neat

Temperatura di conservazione

2-30°C

Stringa SMILE

Oc1cccc2Cc3cccc(O)c3C(=O)c12

InChI

1S/C14H10O3/c15-10-5-1-3-8-7-9-4-2-6-11(16)13(9)14(17)12(8)10/h1-6,15-16H,7H2
NUZWLKWWNNJHPT-UHFFFAOYSA-N

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Descrizione generale

Anthralin (Dithranol) is the synthetic form of chrysarobin. It is widely used as a medication for the human skin affected with psoriasis and in short contact therapy to minimize the staining, irritation, etc.
Pharmaceutical secondary standards for application in quality control, provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards.

Applicazioni

Anthralin (Dithranol) may be used as a pharmaceutical reference standard for the quantification of the analyte in pharmaceutical formulations using high pressure liquid chromatography.
These Secondary Standards are qualified as Certified Reference Materials. These are suitable for use in several analytical applications including but not limited to pharma release testing, pharma method development for qualitative and quantitative analyses, food and beverage quality control testing, and other calibration requirements.

Risultati analitici

These secondary standards offer multi-traceability to the USP, EP and BP primary standards, where they are available.

Altre note

This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis.

Nota a piè di pagina

To see an example of a Certificate of Analysis for this material enter LRAA6122 in the Documents slot below. This is an example certificate only and may not be the lot that you receive.

Pittogrammi

Exclamation mark

Avvertenze

Warning

Indicazioni di pericolo

Classi di pericolo

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

Organi bersaglio

Respiratory system

Codice della classe di stoccaggio

11 - Combustible Solids

Classe di pericolosità dell'acqua (WGK)

WGK 3

Punto d’infiammabilità (°F)

Not applicable

Punto d’infiammabilità (°C)

Not applicable


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High-pressure liquid chromatographic determination of anthralin in ointments
Caron C-J, et al.
Journal of Pharmaceutical Sciences, 70(11), 1205-1207 (1981)
Psoriasis and Psoriatic Arthritis: An Integrated Approach, 70(11), 1205-1207 (2005)

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