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PHR1530

Supelco

Acetaminophen Related Compound D

Pharmaceutical Secondary Standard; Certified Reference Material

Sinonimo/i:

Acetanilide, N-Phenylacetamide

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About This Item

Formula condensata:
CH3CONHC6H5
Numero CAS:
Peso molecolare:
135.16
Beilstein:
606468
Numero CE:
Numero MDL:
Codice UNSPSC:
41116107
ID PubChem:
NACRES:
NA.24

Grado

certified reference material
pharmaceutical secondary standard

Livello qualitativo

agenzia

traceable to USP 1003042

Densità del vapore

4.65 (vs air)

Tensione di vapore

1 mmHg ( 114 °C)

Descrizione

API family: acetaminophen

Famiglia di API

acetaminophen, paracetamol

CdA

current certificate can be downloaded

Temp. autoaccensione

1004 °F

Confezionamento

pkg of 200 mg

tecniche

HPLC: suitable
gas chromatography (GC): suitable

P. eboll.

304 °C (lit.)

Punto di fusione

113-115 °C (lit.)

applicazioni

pharmaceutical (small molecule)

Formato

neat

Temperatura di conservazione

2-30°C

Stringa SMILE

CC(=O)Nc1ccccc1

InChI

1S/C8H9NO/c1-7(10)9-8-5-3-2-4-6-8/h2-6H,1H3,(H,9,10)
FZERHIULMFGESH-UHFFFAOYSA-N

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Descrizione generale

This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis.

Pharmaceutical secondary standards for application in quality control, provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards.

It is an impurity of the widely used antipyretic and analgesic drug acetaminophen, also known as paracetamol.

Applicazioni

This pharmaceutical secondary standard can also be used as follows:

  • Detection and quantification of paracetamol, phenylephrine hydrochloride, and paracetamol impurities in pharmaceutical formulations using four chemometric-based spectrophotometric methods
  • Simultaneous determination of paracetamol and phenylephrine hydrochloride in the presence of paracetamol-related impurities using capillary zone electrophoresis (CZE) in their combined tablet forms

Risultati analitici

These secondary standards offer multi-traceability to the USP, EP and BP primary standards, where they are available.

Nota a piè di pagina

To see an example of a Certificate of Analysis for this material enter LRAA3648 in the slot below. This is an example certificate only and may not be the lot that you receive.

Prodotti consigliati

Find a digital Reference Material for this product available on our online platform ChemisTwin® for NMR. You can use this digital equivalent on ChemisTwin® for your sample identity confirmation and compound quantification (with digital external standard). An NMR spectrum of this substance can be viewed and an online comparison against your sample can be performed with a few mouseclicks. Learn more here and start your free trial.

Prodotti correlati

N° Catalogo
Descrizione
Determinazione del prezzo

Pittogrammi

Exclamation mark

Avvertenze

Warning

Indicazioni di pericolo

Consigli di prudenza

Classi di pericolo

Acute Tox. 4 Oral

Codice della classe di stoccaggio

11 - Combustible Solids

Classe di pericolosità dell'acqua (WGK)

WGK 1

Punto d’infiammabilità (°F)

321.8 °F - closed cup

Punto d’infiammabilità (°C)

161 °C - closed cup


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Capillary zone electrophoresis as a quality assessment tool of paracetamol and phenylephrine hydrochloride in presence of paracetamol impurities
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Journal of chromatographic science, 50(4), 335-342 (2012-03-13)
Determination of acetaminophen and its main impurities: 4-nitrophenol, 4'-chloroacetanilide, as well as 4-aminophenol and its degradation products, p-benzoquinone and hydroquinone has been developed and validated by a new high-performance liquid chromatography method. Chromatographic separation has been obtained on a Hypersil
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