PHR1379

Atropine Sulfate

Pharmaceutical Secondary Standard; Certified Reference Material

• Sinonimo/i: Atropine sulfate salt monohydrate, α-(Hydroxymethyl)benzeneacetic acid 8-methyl-8-azabicyclo[3.2.1]oct-3-yl ester, Tropine tropate
• Formula condensata: (C₁₇H₂₃NO₃)₂ · H₂SO₄ · H₂O
• Numero CAS: 5908-99-6
• Peso molecolare: 694.83
• Beilstein: 6109275
• Numero CE: 200-235-0
• Numero MDL: MFCD00074815
• Codice UNSPSC: 41116107
• ID PubChem: 329823356
• NACRES: NA.24

Proprietà

• Grado: certified reference material; pharmaceutical secondary standard
• Livello qualitativo: 300
• agenzia: traceable to BP 23; traceable to Ph. Eur. A1400000; traceable to USP 1045009
• Famiglia di API: atropine
• CdA: current certificate can be downloaded
• tecniche: HPLC: suitable; gas chromatography (GC): suitable
• Punto di fusione: 189-192 °C (A) (lit.)
• applicazioni: pharmaceutical (small molecule)
• Formato: neat
• Temperatura di conservazione: 2-8°C
• Stringa SMILE: O.OS(O)(=O)=O.CN1[C@H]2CC[C@@H]1C[C@@H](C2)OC(=O)C(CO)c3ccccc3.CN4[C@H]5CC[C@@H]4C[C@@H](C5)OC(=O)C(CO)c6ccccc6
• InChI: 1S/2C17H23NO3.H2O4S.H2O/c2*1-18-13-7-8-14(18)10-15(9-13)21-17(20)16(11-19)12-5-3-2-4-6-12;1-5(2,3)4;/h2*2-6,13-16,19H,7-11H2,1H3;(H2,1,2,3,4);1H2/t2*13-,14+,15+,16?;;; JPKKQJKQTPNWTR-CHYDPLAESA-N
• Informazioni sul gene: human ... CHRM1(1128) , CHRM2(1129) , CHRM3(1131)

Descrizione

Descrizione generale

Pharmaceutical secondary standards for application in quality control, provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards.
Atropine Sulfate is an alkaloid extracted from belladonna herb. It is a cholinergic drug, administered as an anti-arrhythmic medicine.[1]

Applicazioni

Atropine Sulfate may be used as a pharmaceutical reference standard for the determination of the analyte in pharmaceutical formulations by electrophoresis[2] and chromatography techniques.[3][4]

These Secondary Standards are qualified as Certified Reference Materials. These are suitable for use in several analytical applications including but not limited to pharma release testing, pharma method development for qualitative and quantitative analyses, food and beverage quality control testing, and other calibration requirements.

Azioni biochim/fisiol

Competitive nonselective antagonist at central and peripheral muscarinic acetylcholine receptors.

Nota a piè di pagina

To see an example of a Certificate of Analysis for this material enter LRAC4087 in the slot below. This is an example certificate only and may not be the lot that you receive.

Informazioni sulla sicurezza

• Pittogrammi: GHS06
• Avvertenze: Danger
• Indicazioni di pericolo: H300 + H330
• Consigli di prudenza: P260 - P264 - P271 - P284 - P304 + P340 + P310 - P403 + P233
• Classi di pericolo: Acute Tox. 2 Inhalation - Acute Tox. 2 Oral
• Codice della classe di stoccaggio: 6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials
• Classe di pericolosità dell'acqua (WGK): WGK 3
• Punto d’infiammabilità (°F): Not applicable
• Punto d’infiammabilità (°C): Not applicable