P3502

Phloroglucinol

Used to detect the presence of wood fiber.

• Sinonimo/i: 1,3,5-Trihydroxybenzene
• Formula empirica (notazione di Hill): C₆H₆O₃
• Numero CAS: 108-73-6
• Peso molecolare: 126.11
• Beilstein: 1341907
• Numero CE: 203-611-2
• Numero MDL: MFCD00002286
• Codice UNSPSC: 12171500
• ID PubChem: 24898417
• NACRES: NA.47

Proprietà

• Livello qualitativo: 100
• Forma fisica: powder or crystals
• Punto di fusione: 215-220 °C
• Solubilità: ethanol: 50 mg/mL (clear to hazy)
• applicazioni: diagnostic assay manufacturing; hematology; histology
• Temperatura di conservazione: room temp
• Stringa SMILE: Oc1cc(O)cc(O)c1
• InChI: 1S/C6H6O3/c7-4-1-5(8)3-6(9)2-4/h1-3,7-9H; QCDYQQDYXPDABM-UHFFFAOYSA-N

Descrizione

Descrizione generale

Phloroglucinol (phlo) is a phenol derivative that shows a cytoprotective effect from oxidative damage by enhancing the activity of cellular catalase. It can also be used to prepare synthetic analogs of A-type proanthocyanidins (PACs) such as 2,8-dioxabicyclo[3.3.1]nonane derivatives by reacting with the corresponding flavylium salts. Phlo can react with benzaldehyde derivatives to form phloroglucinol-based microporous polymeric organic frameworks (phlo-POF) with potential applications in ion exchange and gas adsorption.

Phloroglucinol is an antispasmodic and a derivative of phenol.

Applicazioni

Phloroglucinol has been used to prevent hyperhydricity by promoting the lignification of shoots. It has also been used in PG (phloroglucinol)-sucrose treatments for the growth and development of in vitro derived shoot tips. Phloroglucinol has been used to stain root sections. It has also been used to stain plant sections to identify plant materials like lignin.

Phloroglucinol has been used to stain root sections. It has also been used to stain plant sections to identify plant materials like lignin.

Azioni biochim/fisiol

Phloroglucinol displays antispasmodic activity. It is a trihydroxybenzene with antithrombotic, profibrinolytic, antimicrobial, antimalarial, cancer chemopreventive, anti-HIV, and anti-leishmanial activities. Phloroglucinol (PG) is a biosynthetic precursor of the 2,4-diacetylphloroglucinol (DAPG) an antibiotic against soil-borne diseases. Phloroglucinol is a useful intermediate because it is polyfunctional.

Informazioni sulla sicurezza

• Pittogrammi: GHS07
• Avvertenze: Warning
• Indicazioni di pericolo: H315,H317,H319,H335
• Consigli di prudenza: P261 - P264 - P271 - P280 - P302 + P352 - P305 + P351 + P338
• Classi di pericolo: Eye Irrit. 2 - Skin Irrit. 2 - Skin Sens. 1 - STOT SE 3
• Organi bersaglio: Respiratory system
• Codice della classe di stoccaggio: 11 - Combustible Solids
• Classe di pericolosità dell'acqua (WGK): WGK 2
• Punto d’infiammabilità (°F): Not applicable
• Punto d’infiammabilità (°C): Not applicable
• Dispositivi di protezione individuale: Eyeshields, Gloves, type N95 (US)