The I0328000 product is an analytical standard supplied by the EP. It is in powder form. Alternatively, product I9890 (also in powder form) is a research-grade option. Neither of these products would be suitable for human use and are intended for laboratory research only. See the link below to the general research-grade product:
https://www.sigmaaldrich.com/product/sigma/i9890
I0328000
Iobenguane sulfate
European Pharmacopoeia (EP) Reference Standard
Sinonimo/i:
m-Iodobenzylguanidine hemisulfate salt, MIBG
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About This Item
Formula condensata:
C8H10IN3 · 1/2H2SO4
Numero CAS:
Peso molecolare:
324.13
Numero MDL:
Codice UNSPSC:
41116107
ID PubChem:
NACRES:
NA.24
Prezzi e disponibilità al momento non sono disponibili
Prodotti consigliati
Grado
pharmaceutical primary standard
Famiglia di API
iobenguane
Produttore/marchio commerciale
EDQM
applicazioni
pharmaceutical (small molecule)
Formato
neat
Temperatura di conservazione
2-8°C
Stringa SMILE
OS(O)(=O)=O.NC(=N)NCc1cccc(I)c1.NC(=N)NCc2cccc(I)c2
InChI
1S/2C8H10IN3.H2O4S/c2*9-7-3-1-2-6(4-7)5-12-8(10)11;1-5(2,3)4/h2*1-4H,5H2,(H4,10,11,12);(H2,1,2,3,4)
XNACDNPGABUBFR-UHFFFAOYSA-N
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Descrizione generale
This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia.
Applicazioni
Iobenguane sulfate EP Reference standard, intended for use in laboratory tests only as specifically prescribed in the European Pharmacopoeia.
Confezionamento
The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity, please visit the EDQM reference substance catalogue.
Altre note
Sales restrictions may apply.
Codice della classe di stoccaggio
11 - Combustible Solids
Classe di pericolosità dell'acqua (WGK)
WGK 3
Punto d’infiammabilità (°F)
Not applicable
Punto d’infiammabilità (°C)
Not applicable
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Certificati d'analisi (COA)
Lot/Batch Number
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I documenti relativi ai prodotti acquistati recentemente sono disponibili nell’Archivio dei documenti.
Radioiodinated metaiodobenzylguanidine (MIBG): radiochemistry, biology, and pharmacology.
Vallabhajosula S and Nikolopoulou A
Seminars in Nuclear Medicine, 41(5), 324-333 (2011)
Yan Su et al.
International journal of molecular medicine, 34(3), 842-848 (2014-06-28)
The aim of the present study was to investigate the effects of meta-iodobenzylguanidine (MIBG) on the invasive properties of hepatocellular carcinoma (HCC) cells and examine whether these effects are due to the ability of MIBG to inhibit arginine-specific mono-ADP-ribosylation. Samples
Shih-ying Huang et al.
Molecular imaging and biology : MIB : the official publication of the Academy of Molecular Imaging, 17(2), 284-294 (2014-08-26)
Iodine-131-m-iodobenzylguanidine ([(131)I]mIBG)-targeted radionuclide therapy (TRT) is a standard treatment for recurrent or refractory neuroblastoma with response rates of 30-40 %. The aim of this study is to demonstrate patient-specific dosimetry using quantitative [(124)I]mIBG positron emission tomography/X-ray computed tomography (PET/CT) imaging
Lang Rao et al.
EMBO reports, 22(2), e50613-e50613 (2020-12-22)
One major factor that contributes to the virulence of Pseudomonas aeruginosa is its ability to reside and replicate unchallenged inside airway epithelial cells. The mechanism by which P. aeruginosa escapes destruction by intracellular host defense mechanisms, such as autophagy, is not
Shohei Shinozaki et al.
Science signaling, 7(351), ra106-ra106 (2014-11-13)
Inflammation increases the abundance of inducible nitric oxide synthase (iNOS), leading to enhanced production of nitric oxide (NO), which can modify proteins by S-nitrosylation. Enhanced NO production increases the activities of the transcription factors p53 and nuclear factor κB (NF-κB)
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Hi, I am looking for MIBG solution with non-radioactive iodine solution which can be used for research purposes in CT scans. Could you suggest any solution? Thanks a lot.
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