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BCR096

Dibenzo[a,l]pyrene

BCR®, certified reference material

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About This Item

Formula empirica (notazione di Hill):
C24H14
Numero CAS:
191-30-0
Peso molecolare:
302.37
Beilstein:
2054068
Numero MDL:
MFCD00467035
Codice UNSPSC:
41116107
ID PubChem:
329774220
NACRES:
NA.24

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Grado

certified reference material

agenzia

BCR®

Produttore/marchio commerciale

JRC

tecniche

HPLC: suitable
gas chromatography (GC): suitable

Formato

neat

Temperatura di conservazione

2-8°C

Stringa SMILE

c1ccc2c(c1)cc3ccc4cccc5c6ccccc6c2c3c45

InChI

1S/C24H14/c1-2-8-18-16(6-1)14-17-13-12-15-7-5-11-20-19-9-3-4-10-21(19)24(18)23(17)22(15)20/h1-14H
JNTHRSHGARDABO-UHFFFAOYSA-N

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Risultati analitici

For more information please see:
BCR096

Note legali

BCR is a registered trademark of European Commission

Pittogrammi

Health hazardCorrosion
GHS08,GHS05

Avvertenze

Danger

Indicazioni di pericolo

H318,H341,H350

Classi di pericolo

Carc. 1B - Eye Dam. 1 - Muta. 2

Codice della classe di stoccaggio

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

Classe di pericolosità dell'acqua (WGK)

WGK 3

Punto d’infiammabilità (°F)

Not applicable

Punto d’infiammabilità (°C)

Not applicable

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Certificati d'analisi (COA)

Lot/Batch Number

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David M DeMarini et al.
Mutation research, 714(1-2), 17-25 (2011-06-22)
Benzo[a]pyrene (BP) and dibenzo[a,l]pyrene (DBP) are two polycyclic aromatic hydrocarbons (PAHs) that exhibit distinctly different mutagenicity and carcinogenicity profiles. Although some studies show that these PAHs produce unstable DNA adducts, conflicting data and arguments have been presented regarding the relative
Lyndsey E Shorey et al.
Toxicology and applied pharmacology, 270(1), 60-69 (2013-04-10)
Cruciferous vegetable components have been documented to exhibit anticancer properties. Targets of action span multiple mechanisms deregulated during cancer progression, ranging from altered carcinogen metabolism to the restoration of epigenetic machinery. Furthermore, the developing fetus is highly susceptible to changes
David J Castro et al.
Cancer prevention research (Philadelphia, Pa.), 1(2), 128-134 (2009-01-14)
Dibenzo(a,l)pyrene (DBP) is among the most potent carcinogenic polycyclic aromatic hydrocarbons. Previously, we showed that DBP administration to pregnant mice resulted in high mortality of offspring from an aggressive T-cell lymphoma. All mice that survive to 10 months of age
David E Williams
Comparative biochemistry and physiology. Toxicology & pharmacology : CBP, 155(1), 121-127 (2011-06-28)
Rainbow trout (Oncorhynchus mykiss) are an outstanding model of liver cancer induction by environmental chemicals and development of strategies for chemoprevention. Trout have critical and unique advantages allowing for cancer studies with 40,000 animals to determine dose-response at levels orders
Yijin Tang et al.
Biochemistry, 51(48), 9751-9762 (2012-11-06)
The most potent tumorigen identified among the polycyclic aromatic hydrocarbons (PAH) is the nonplanar fjord region dibenzo[a,l]pyrene (DB[a,l]P). It is metabolically activated in vivo through the widely studied diol epoxide (DE) pathway to form covalent adducts with DNA bases, predominantly
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Articoli

Efficient PAH Analysis (EU 15+1) using an Ascentis® Express PAH HPLC Column

This application note describes the fast and efficient separation of the EU’s list of 15 + 1 polynuclear aromatic hydrocarbons (PAHs) using Ascentis® Express PAH HPLC column.

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