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Documenti fondamentali

81172

Sigma-Aldrich

Poli(etilenglicole)

tested according to Ph. Eur., 400

Sinonimo/i:

PEG

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About This Item

Formula condensata:
H(OCH2CH2)nOH
Numero CAS:
Numero MDL:
Codice UNSPSC:
12352104
ID PubChem:
NACRES:
NA.21

CHF 103.00


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agenzia

tested according to Ph. Eur.

Livello qualitativo

Stato

liquid

PM

380-420

applicazioni

pharmaceutical (small molecule)

Stringa SMILE

C(CO)O

InChI

1S/C2H6O2/c3-1-2-4/h3-4H,1-2H2
LYCAIKOWRPUZTN-UHFFFAOYSA-N

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Descrizione generale

Polyethylene glycol (PEG) is a polyether compound[1] with repeated ethylene glycol units[-(CH2CH2O)n].[2]

Applicazioni

Poly(ethylene glycol) has been used as a liquid medium to prepare shear thickening fluid (STF) by directly mixing it with fumica silica.[3][4][5]

Azioni biochim/fisiol

Polyethylene glycol (PEG) is a synthetic polymer[6] and is used as an additive in food, cosmetics, and pharmaceuticals.[1] It is also involved in biomedical applications like biosensing, imaging, and tissue engineering. PEG is used as a gold standard in bioconjugation and nanomedicine thereby increasing blood circulation time and improving drug efficacy. PEG-conjugated drugs are approved by the U.S. Food and Drug Administration (FDA). They are considered safe for use in humans.[6] PEG reduces the liver uptake and repels protein adsorption, which makes it useful in nanocoating.[7]

Codice della classe di stoccaggio

10 - Combustible liquids

Classe di pericolosità dell'acqua (WGK)

WGK 1

Punto d’infiammabilità (°F)

Not applicable

Punto d’infiammabilità (°C)

Not applicable

Dispositivi di protezione individuale

Eyeshields, Gloves


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Certificati d'analisi (COA)

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The stab resistance of fabrics impregnated with shear thickening fluids including various particle size of additives
Gurgen S and Kucshan MC
Composites Part A: Applied Science and Manufacturing, 94, 50-60 (2017)
The rheology of shear thickening fluids with various ceramic particle additives
Gurgen S, et al.
Materials & Design, 104, 312-319 (2016)
The ballistic performance of aramid based fabrics impregnated with multi-phase shear thickening fluids
Gurgen S and Kucshan MC
Polymer Testing, 64, 296-306 (2017)
Thai Thanh Hoang Thi et al.
Polymers, 12(2) (2020-02-07)
Poly(ethylene glycol) (PEG) is widely used as a gold standard in bioconjugation and nanomedicine to prolong blood circulation time and improve drug efficacy. The conjugation of PEG to proteins, peptides, oligonucleotides (DNA, small interfering RNA (siRNA), microRNA (miRNA)) and nanoparticles
Anisha A D'souza et al.
Expert opinion on drug delivery, 13(9), 1257-1275 (2016-04-28)
Polyethylene glycol (PEG) is a polymer of choice in drug delivery systems. This USFDA-approved polymer is popular due to its tunable properties and well-established safety profile: prime requisites considered during the selection of any excipient in formulation development. The unique

Questions

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  1. How is shipping temperature determined? And how is it related to the product storage temperature?

    1 answer
    1. Products may be shipped at a different temperature than the recommended long-term storage temperature. If the product quality is sensitive to short-term exposure to conditions other than the recommended long-term storage, it will be shipped on wet or dry-ice. If the product quality is NOT affected by short-term exposure to conditions other than the recommended long-term storage, it will be shipped at ambient temperature. As shipping routes are configured for minimum transit times, shipping at ambient temperature helps control shipping costs for our customers. For more information, please refer to the Storage and Transport Conditions document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/316/622/storage-transport-conditions-mk.pdf

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  2. How can I determine the shelf life / expiration / retest date of this product?

    1 answer
    1. If this product has an expiration or retest date, it will be shown on the Certificate of Analysis (COA, CofA). If there is no retest or expiration date listed on the product's COA, we do not have suitable stability data to determine a shelf life. For these products, the only date on the COA will be the release date; a retest, expiration, or use-by-date will not be displayed.
      For all products, we recommend handling per defined conditions as printed in our product literature and website product descriptions. We recommend that products should be routinely inspected by customers to ensure they perform as expected.
      For products without retest or expiration dates, our standard warranty of 1 year from the date of shipment is applicable.
      For more information, please refer to the Product Dating Information document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/449/386/product-dating-information-mk.pdf

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