68923

Esculetin

analytical standard

• Sinonimo/i: 6,7-Dihydroxycoumarin, Cichorigenin, Esculetin
• Formula empirica (notazione di Hill): C₉H₆O₄
• Numero CAS: 305-01-1
• Peso molecolare: 178.14
• Beilstein: 152788
• Numero CE: 206-161-5
• Numero MDL: MFCD00006874
• Codice UNSPSC: 12352200
• ID PubChem: 329761226
• NACRES: NA.24

Proprietà

• Grado: analytical standard
• Livello qualitativo: 100
• Saggio: ≥97.5% (HPLC); 97.5-102.5% (NT)
• Durata: limited shelf life, expiry date on the label
• Punto di fusione: 271-273 °C (lit.)
• Formato: neat
• Stringa SMILE: Oc1cc2OC(=O)C=Cc2cc1O
• InChI: 1S/C9H6O4/c10-6-3-5-1-2-9(12)13-8(5)4-7(6)11/h1-4,10-11H; ILEDWLMCKZNDJK-UHFFFAOYSA-N

Descrizione

Descrizione generale

Esculetin is a derivative of coumarin, found in various plant species including Cichorium intybus (chicory), Bougainvillea spectabilis, Artemisia capillaris, etc and leaves of Citrus limonia (Rutaceae), Ceratostigma willmottianum, etc. It exhibits multiple pharmacological activities and is found to be a potent inhibitor of cyclooxygenase, 5-lipoxygenase, 12-lipoxygenase, catechol-O-methyl transferase, NADPH oxidase and xanthine oxidase enzymes.

Applicazioni

Esculetin may be used as an analytical reference standard for the determination of the analyte in biological and water samples by chromatography-based techniques. It may also be used as a standard in the quantification of the analyte in traditional herbal medicines by solid-phase extraction and micellar electrokinetic capillary methods, respectively.

Informazioni sulla sicurezza

• Codice della classe di stoccaggio: 11 - Combustible Solids
• Classe di pericolosità dell'acqua (WGK): WGK 3
• Punto d’infiammabilità (°F): Not applicable
• Punto d’infiammabilità (°C): Not applicable