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Documenti

55443

Supelco

Fenofibrate

analytical standard

Sinonimo/i:

2-[4-(4-Chlorobenzoyl)phenoxy]-2-methylpropanoic acid isopropyl ester

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About This Item

Formula empirica (notazione di Hill):
C20H21ClO4
Numero CAS:
49562-28-9
Peso molecolare:
360.83
Numero CE:
256-376-3
Numero MDL:
MFCD00133314
Codice UNSPSC:
41116107
ID PubChem:
329758114
NACRES:
NA.24

Grado

analytical standard

Livello qualitativo

100

Saggio

≥99.0% (HPLC)

Durata

limited shelf life, expiry date on the label

tecniche

HPLC: suitable
gas chromatography (GC): suitable

Impurezze

≤0.3% water

applicazioni

forensics and toxicology
pharmaceutical (small molecule)

Formato

neat

Stringa SMILE

CC(C)OC(=O)C(C)(C)Oc1ccc(cc1)C(=O)c2ccc(Cl)cc2

InChI

1S/C20H21ClO4/c1-13(2)24-19(23)20(3,4)25-17-11-7-15(8-12-17)18(22)14-5-9-16(21)10-6-14/h5-13H,1-4H3
YMTINGFKWWXKFG-UHFFFAOYSA-N

Informazioni sul gene

human ... PPARA(5465)

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Applicazioni

Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

Pittogrammi

Health hazard
GHS08

Avvertenze

Warning

Indicazioni di pericolo

H373

Consigli di prudenza

P260 - P314 - P501

Classi di pericolo

STOT RE 2 Oral

Organi bersaglio

Liver

Codice della classe di stoccaggio

11 - Combustible Solids

Classe di pericolosità dell'acqua (WGK)

WGK 1

Punto d’infiammabilità (°F)

Not applicable

Punto d’infiammabilità (°C)

Not applicable

Scegli una delle versioni più recenti:

Certificati d'analisi (COA)

Lot/Batch Number
BCCK5234
BCCF4854
BCBW8695
BCBS7222V
BCBQ9939V

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Supelco

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Sigma-Aldrich

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PloS one, 9(8), e104925-e104925 (2014-08-21)
Liver is a major regulator of lipid metabolism and adaptation to fasting, a process involving PPARalpha activation. We recently showed that the Vnn1 gene is a PPARalpha target gene in liver and that release of the Vanin-1 pantetheinase in serum
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Fenofibrate is a fibric acid derivative indicated for the treatment of severe hypertriglyceridaemia and mixed dyslipidaemia in patients who have not responded to nonpharmacological therapies. The lipid-modifying effects of fenofibrate are mediated by the activation of peroxisome proliferator-activated receptor-α. Fenofibrate
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Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism, 34(4), 646-653 (2014-01-16)
The strategies to protect against the disrupted blood-brain barrier (BBB) in HIV-1 infection are not well developed. Therefore, we investigated the potential of peroxisome proliferator-activated receptor (PPAR) agonists to prevent enhanced BBB permeability induced by HIV-1-specific protein Tat. Exposure to
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