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Documenti fondamentali

45753

Supelco

Flusilazole

PESTANAL®, analytical standard

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About This Item

Formula empirica (notazione di Hill):
C16H15F2N3Si
Numero CAS:
Peso molecolare:
315.39
Beilstein:
5824097
Numero MDL:
Codice UNSPSC:
41116107
ID PubChem:
NACRES:
NA.24

Grado

analytical standard

Livello qualitativo

Nome Commerciale

PESTANAL®

Durata

limited shelf life, expiry date on the label

tecniche

HPLC: suitable
gas chromatography (GC): suitable

applicazioni

agriculture
cleaning products
cosmetics
environmental
food and beverages
personal care

Formato

neat

Stringa SMILE

C[Si](Cn1cncn1)(c2ccc(F)cc2)c3ccc(F)cc3

InChI

1S/C16H15F2N3Si/c1-22(12-21-11-19-10-20-21,15-6-2-13(17)3-7-15)16-8-4-14(18)5-9-16/h2-11H,12H2,1H3
FQKUGOMFVDPBIZ-UHFFFAOYSA-N

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Descrizione generale

Flusilazole is an organosilicon fungicide, which belongs to the class of sterol demethylation inhibitors. Its mode of action involves the inhibition of lanosterol 1,4-α-demethylation in fungal sterol biosynthesis.

Applicazioni

Flusilazole may be used as a reference standard for the determination of flusilazole in water samples using solid-phase extraction (SPE) method using multi-walled carbon nanotubes as adsorbent coupled with high-performance liquid chromatography (HPLC).
Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

Note legali

PESTANAL is a registered trademark of Merck KGaA, Darmstadt, Germany

Avvertenze

Danger

Indicazioni di pericolo

Classi di pericolo

Acute Tox. 4 Oral - Aquatic Chronic 2 - Carc. 2 - Repr. 1B

Codice della classe di stoccaggio

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

Classe di pericolosità dell'acqua (WGK)

WGK 3

Punto d’infiammabilità (°F)

Not applicable

Punto d’infiammabilità (°C)

Not applicable

Dispositivi di protezione individuale

Eyeshields, Faceshields, Gloves, type P3 (EN 143) respirator cartridges


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Certificati d'analisi (COA)

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Sensitivity of Venturia inaequalis isolates from British Columbia to flusilazole and myclobutanil.
Sholberg LP and Haag DP
Canadian Journal of Plant Pathology, 15(2), 102-106 (1993)
Determination of pyrazole and pyrrole pesticides in environmental water samples by solid-phase extraction using multi-walled carbon nanotubes as adsorbent coupled with high-performance liquid chromatography.
Ma J, et al.
Journal of Chromatographic Science, 53(2), 380-384 (2014)
B Grausem et al.
The Plant journal : for cell and molecular biology, 7(5), 761-770 (1995-05-01)
Nicotiana tabacum protoplasts have been transformed by Agrobacterium tumefaciens containing a T-DNA in which the gene CYP51A1 encoding lanosterol-14-demethylase (LAN14DM) from Saccharomyces cerevisiae is under the control of a cauliflower mosaic virus (CaMV) 35S promoter. Two transformants strongly expressed the
Amina T Farag et al.
Birth defects research. Part B, Developmental and reproductive toxicology, 80(1), 12-17 (2006-12-26)
The developmental toxicity of flusilazole was studied in CD-1 mice after oral administration. Pregnant mice were given flusilazole at doses of 0 (corn oil), 10, 20, and 40 mg/kg/day, by gavage, on gestational days (GD) 6-15. Maternal toxicity, as evidenced
P T Theunissen et al.
Toxicology and applied pharmacology, 262(3), 330-340 (2012-05-29)
Alternative assays for developmental toxicity testing are needed to reduce animal use in regulatory toxicology. The in vitro murine neural embryonic stem cell test (ESTn) was designed as an alternative for neurodevelopmental toxicity testing. The integration of toxicogenomic-based approaches may

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