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00390580

Rosmarinic acid

primary reference standard

Sinonimo/i:

(R)-O-(3,4-Dihydroxycinnamoyl)-3-(3,4- dihydroxyphenyl)lactic acid, 3,4-Dihydroxycinnamic acid (R)-1-carboxy-2-(3,4-dihydroxyphenyl)ethyl ester

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CHF 461.00

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25 MG
CHF 461.00

About This Item

Formula empirica (notazione di Hill):
C18H16O8
Numero CAS:
20283-92-5
Peso molecolare:
360.31
Beilstein:
2227587
Numero MDL:
MFCD00017740
Codice UNSPSC:
85151701
ID PubChem:
329747058
NACRES:
NA.24

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Grado

primary reference standard

Durata

limited shelf life, expiry date on the label

Produttore/marchio commerciale

HWI

tecniche

HPLC: suitable
gas chromatography (GC): suitable

Punto di fusione

171-175 °C (lit.)

Temperatura di conservazione

−20°C

Stringa SMILE

OC(=O)[C@@H](Cc1ccc(O)c(O)c1)OC(=O)\C=C\c2ccc(O)c(O)c2

InChI

1S/C18H16O8/c19-12-4-1-10(7-14(12)21)3-6-17(23)26-16(18(24)25)9-11-2-5-13(20)15(22)8-11/h1-8,16,19-22H,9H2,(H,24,25)/b6-3+/t16-/m1/s1
DOUMFZQKYFQNTF-WUTVXBCWSA-N

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Categorie correlate

Descrizione generale

Produced and qualified by HWI pharma services GmbH.
Exact content by quantitative NMR can be found on the certificate.

Applicazioni

Reference standard in the analysis of herbal medicinal products.

Azioni biochim/fisiol

Rosmarinic acid has shown to contain antioxidant and anti-inflammatory activities. Possesses promising physiological actions related to cognitive performance, Alzheimer′s disease prevention, kidney disease treatment, cardioprotection and cancer chemoprevention.

Altre note

This compound is commonly found in plants of the genus: melissa mentha salvia thymus

Codice della classe di stoccaggio

11 - Combustible Solids

Classe di pericolosità dell'acqua (WGK)

WGK 3

Punto d’infiammabilità (°F)

Not applicable

Punto d’infiammabilità (°C)

Not applicable

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Certificati d'analisi (COA)

Lot/Batch Number
HWI02735-1
HWI02133-1
HWI00981
HWI00131-4
HWI00131-3

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Juan A Martín et al.
PloS one, 8(2), e56987-e56987 (2013-03-08)
Efforts to introduce pathogen resistance into landscape tree species by breeding may have unintended consequences for fungal diversity. To address this issue, we compared the frequency and diversity of endophytic fungi and defensive phenolic metabolites in elm (Ulmus spp.) trees
Eun-Ju Yang et al.
Journal of cellular physiology, 228(5), 975-982 (2012-10-09)
High mobility group box 1 (HMGB1) protein is a crucial cytokine that mediates response to infection, injury, and inflammation. Rosmarinic acid (RA) is an important component of the leaves of Perilla frutescens and has neuroprotective, anti-microbial, anti-oxidant, and anti-cancer effects
Maike Petersen et al.
Phytochemistry, 62(2), 121-125 (2002-12-17)
Rosmarinic acid is an ester of caffeic acid and 3,4-dihydroxyphenyllactic acid. It is commonly found in species of the Boraginaceae and the subfamily Nepetoideae of the Lamiaceae. However, it is also found in species of other higher plant families and
Anja Klančnik et al.
PloS one, 7(12), e51800-e51800 (2013-01-04)
Campylobacter is a major foodborne pathogen and alternative antimicrobials are needed to prevent or decrease Campylobacter contamination in foods or food producing animals. The objectives of this study are to define the anti-Campylobacter activities of natural phenolic compounds of plant
Cristina Airoldi et al.
Chemistry, an Asian journal, 8(3), 596-602 (2013-01-11)
Amyloid peptides, Aβ1-40 and Aβ1-42, represent major molecular targets to develop potential drugs and diagnostic tools for Alzheimer's Disease (AD). In fact, oligomeric and fibrillar aggregates generated by these peptides are amongst the principal components of amyloid plaques found post
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