MABN369

Anti-Neuroglobin Antibody, clone 6G1.1

clone 6G1.1, from mouse

• Sinonimo/i: Neuroglobin
• Codice UNSPSC: 12352203
• eCl@ss: 32160702
• NACRES: NA.41

Proprietà

• Origine biologica: mouse
• Livello qualitativo: 100
• Forma dell’anticorpo: purified immunoglobulin
• Tipo di anticorpo: primary antibodies
• Clone: 6G1.1, monoclonal
• Reattività contro le specie: human
• tecniche: immunohistochemistry: suitable; western blot: suitable
• Isotipo: IgG2bκ
• N° accesso NCBI: NP_067080
• N° accesso UniProt: Q9NPG2
• Condizioni di spedizione: wet ice
• modifica post-traduzionali bersaglio: unmodified
• Informazioni sul gene: human ... NGB(58157)

Descrizione

Descrizione generale

Neuroglobin protein encoded by the gene NGB, is involved in oxygen transport in the brain. Neuroglobin is also important for neuroprotection during oxidative stress. Additionally, Neuroglobin has anti-apoptotic activity by reseting the mitochondrial membrane tigger level for cytochrome C release and the commitment to apoptosis. Neuroglobin is localized to the perikaryon, cytoplasm, and mitochondrion. Neuroglobin is predominantly expressed in the brain with strongest expression in the frontal lobe and the subthalamic nucleus and thalamus.

Immunogeno

GST-tagged recombinant protein corresponding to the N-terminus of human Neuroglobin.

Applicazioni

Detect Neuroglobin using this mouse monoclonal antibody, Anti-Neuroglobin Antibody, clone 6G1.1 validated for use in western blotting & IHC.

Immunohistochemistry Analysis: A 1:50 dilution from a representative lot detected Neuroglobin in human thalamus and human frontal lobe tissue.

Qualità

Evaluated by Western Blotting in human cortex tissue lysate.

Western Blotting Analysis: 1.0 µg/mL of this antibody detected Neuroglobin in 10 µg of human cortex tissue lysate.

Descrizione del bersaglio

~17 kDa observed

Stato fisico

Format: Purified

Altre note

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

Informazioni sulla sicurezza

• Codice della classe di stoccaggio: 12 - Non Combustible Liquids
• Classe di pericolosità dell'acqua (WGK): WGK 1
• Punto d’infiammabilità (°F): Not applicable
• Punto d’infiammabilità (°C): Not applicable