MABN2529

Anti-Huntingtin Disease (HD/HTT) Antibody

mouse monoclonal, MW8

• Codice UNSPSC: 12352203
• eCl@ss: 32160702
• NACRES: NA.41

Proprietà

• Nome del prodotto: Anti-HTT Antibody, clone MW8,
• Forma dell’anticorpo: purified antibody
• Clone: MW8; monoclonal
• Purificato mediante: using protein G
• Reattività contro le specie: mouse, mouse, human
• Concentrazione: (Please refer to lot specific datasheet.)
• tecniche: ELISA: suitable; immunocytochemistry: suitable; immunohistochemistry: suitable; immunoprecipitation (IP): suitable; western blot: suitable
• Isotipo: IgG2aκ
• N° accesso UniProt: P42858

Descrizione

Descrizione generale

HD exon-1 67Q aggregate.

Specificità

Clone MW8 is a mouse monoclonal antibody that detects Huntingtin protein. It targets an epitope within nine amino acids in the exon-1 region.

Applicazioni

Immunocytochemistry Analysis: A representative lot detected HTT in Immunocytochemistry applications (Legleiter, J., et. al. (2009). J Biol Chem. 284(32):21647-58).

Immunohistochemistry Analysis: A representative lot detected HTT in Immunohistochemistry applications (Ko, J., et. al. (2001). Brain Res Bull. 56(3-4):319-29).

Western Blotting Analysis: A representative lot detected HTT in Western Blotting applications (Legleiter, J., et. al. (2009). J Biol Chem. 284(32):21647-58).

Enzyme Immunoassay (ELISA) Analysis: A representative lot detected HTT in ELISA applications (Ko, J., et. al. (2001). Brain Res Bull. 56(3-4):319-29).

Immunoprecipitation Analysis: A representative lot immunoprecipitated HTT in Immunoprecipitation applications (Baldo, B., et. al. (2012). Chem Biol. 19(2):264-75).

Western Blotting Analysis: A 1:1,000 dilution from a representative lot detected HTT in Tissue lysate of 9 month-old WT or Q140 KI HD mice.

Qualità

Isotype testing: Identity Confirmation by Isotyping Test.

Isotyping Analysis: The identity of this monoclonal antibody is confirmed by isotyping test to be mouse IgG2a.

Proprietà fisiche

347.6 kDa calclulated

Stato fisico

Purified mouse monoclonal antibody IgG2a in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.

Stoccaggio e stabilità

Stable for 1 year at 2-8°C from date of receipt.

Altre note

Human, Mouse.

Esclusione di responsabilità

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.