8.52052

Fmoc-His(Boc)-OH-CHA

Novabiochem^®

• Sinonimo/i: Fmoc-His(Boc)-OH-CHA, N-α-Fmoc-N-im-t.-Boc-L-histidine cyclohexylammonium salt
• Formula empirica (notazione di Hill): C₂₆H₂₇N₃O₆ · xC₆H₁₃N
• Numero CAS: 210820-99-8
• Peso molecolare: 477.51
• Codice UNSPSC: 12352209

Proprietà

• Nome Commerciale: Novabiochem^®
• Saggio: ≥97% (TLC); ≥97.0% (HPLC)
• Stato: powder
• Impiego in reazioni chimiche: reaction type: Fmoc solid-phase peptide synthesis
• Produttore/marchio commerciale: Novabiochem^®
• applicazioni: peptide synthesis
• Gruppo funzionale: Boc; Fmoc
• Temperatura di conservazione: −20°C (−15°C to −25°C)
• InChI: 1S/C26H27N3O6.C6H13N/c1-26(2,3)35-25(33)29-13-16(27-15-29)12-22(23(30)31)28-24(32)34-14-21-19-10-6-4-8-17(19)18-9-5-7-11-20(18)21;7-6-4-2-1-3-5-6/h4-11,13,15,21-22H,12,14H2,1-3H3,(H,28,32)(H,30,31);6H,1-5,7H2/t22-;/m0./s1; UDEXYAHZNOKVIG-FTBISJDPSA-N

Descrizione

Descrizione generale

The N-im-Boc group is unstable to prolonged treatment with piperidine [1]; the utility of this derivative is therefore limited to the preparation of short sequences by Fmoc SPPS. This derivative is supplied as a CHA-salt.

Associated Protocols and Technical Articles
Cleavage and Deprotection Protocols for Fmoc SPPS

Literature references

^[1] P. Sieber, et al. (1987) Tetrahedron Lett., 28, 6031.

Linkage

Replaces: 04-12-1110

Risultati analitici

Color (visual): white to slight yellow to beige
Appearance of substance (visual): powder
Identity (IR): passes test
Enantiomeric purity: ≥ 99.5 % (a/a)
Purity (TLC(011A)): ≥ 97 %
Purity (TLC(157B)): ≥ 97 %
Assay (HPLC, area%): ≥ 97.0 % (a/a)
Water (K. F.): ≤ 1.00 %

To see the solvent systems used for TLC of Novabiochem^® products please click here.

Note legali

Novabiochem is a registered trademark of Merck KGaA, Darmstadt, Germany

Informazioni sulla sicurezza

• Codice della classe di stoccaggio: 11 - Combustible Solids
• Classe di pericolosità dell'acqua (WGK): WGK 2
• Punto d’infiammabilità (°C): Not applicable