609312

Thyroglobulin, Human Thyroid

• Sinonimo/i: Thyroglobulin, Human Thyroid
• Numero CAS: 9010-34-8
• Codice UNSPSC: 12352202
• NACRES: NA.25

Proprietà

• Origine biologica: human thyroid
• Livello qualitativo: 100
• Saggio: ≥95% (PAGE)
• Forma fisica: lyophilized
• Produttore/marchio commerciale: Calbiochem^®
• Condizioni di stoccaggio: OK to freeze
• Condizioni di spedizione: wet ice
• Temperatura di conservazione: 2-8°C

Descrizione

Descrizione generale

Native thyroglobulin, consisting of two polypeptide monomers of 33 kDa each, purified from human thyroid. This protein is an excellent source of N-linked glycans of various structures, including sialylated core fucose and oligomannose oligosaccharides. Also, Gal-3-SO₄ and GalNAc-6-SO₄ residues located in a single multi-branched complex type glycan have been reported in calf thymus and human proteins.

Native thyroglobulin, consisting of two polypeptide monomers of 330 kDa each, purified from human thyroid. This protein is an excellent source of N-linked glycans of various structures, including sialylated core fucose and oligomannose oligosaccharides. Also, Gal-3-SO₄ and GalNAc-6-SO₄ residues located in a single multi-branched complex type glycan have been reported in calf thymus and human proteins. When subjected to native PAGE this protein shows a band at

~660 kDa, representing the dimeric form, and another band at ~330 kDa, representing the monomeric form.

Attenzione

Toxicity: Standard Handling (A)

Stato fisico

Lyophilized from 20 mM NH₄HCO₃.

Nota sulla preparazione

Prepared from tissues of individuals that have been shown by certified tests to be negative for HBsAg and for antibodies to HIV and HCV.

Ricostituzione

Reconstitute in phosphate buffer, containing 150 mM NaCl, pH >7.0.

Altre note

Rawitch, A.B., et al. 1993. Arch. Biochem. Biophys. 300, 271.
Black, E.G., and Sheppard, M.C. 1991. Clin. Endocrinol. 35, 519.
Spiro, R.G., and Bhoyroo, V.D. 1988. J. Biol. Chem. 263, 14351.

Note legali

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

Informazioni sulla sicurezza

• Codice della classe di stoccaggio: 11 - Combustible Solids
• Classe di pericolosità dell'acqua (WGK): WGK 3