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RAB0458

Sigma-Aldrich

Human Thyroglobulin ELISA Kit

for serum, plasma, cell culture supernatants and urine

Sinonimo/i:

TGF-beta-1, Thyroglobulin

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CHF 501.00

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1 KIT
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About This Item

Codice UNSPSC:
41116158
NACRES:
NA.77

CHF 501.00


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Reattività contro le specie

human

Confezionamento

kit of 96 wells (12 strips x 8 wells)

tecniche

ELISA: suitable
capture ELISA: suitable

input

sample type urine
sample type plasma
sample type cell culture supernatant(s)
sample type serum

assay range

inter-assay cv: <12%
intra-assay cv: <10%
sensitivity: 220 pg/mL
standard curve range: 0.205-50 ng/mL

Metodo di rivelazione

colorimetric

Condizioni di spedizione

wet ice

Temperatura di conservazione

−20°C

Informazioni sul gene

human ... TG(7038)

Descrizione generale

The Human Thyroglobulin ELISA (Enzyme-Linked Immunosorbent Assay) kit is an in vitro enzyme-linked immunosorbent assay for the quantitative measurement of human Thyroglobulin in serum, plasma, cell culture supernatants and urine.

Immunogeno

Recombinant Human Thyroglobulin

Applicazioni

For research use only. Not for use in diagnostic procedures.
Please refer to the attached General ELISA KIT Procedure (sandwich, competitive & Indirect ELISA)
Human Thyroglobulin ELISA Kit has been used to measure the secreted thyroglobulin (TG) level in primary human thyrocytes.[1]

Azioni biochim/fisiol

Thyroglobulin (TG) is a prothyroid hormone. It plays a vital role in production of L-thyroxine (tetraiodothyronine, T4) and L-triiodothyronine (T3) hormones in thyroid gland.[2] Tyrosyls of TG acts as substrate for iodination and hormone formation.[2][3] Serum thyroglobulin level is used as marker of metastases in differentiated thyroid carcinomas.[4] Mutation in the gene is associated with the development of congenital goitrous hypothyroidism and non-endemic simple goitre.[5][6]

Altre note

A sample Certificate of Analysis is available for this product.
Please type the word sample in the text box provided for lot number.

I componenti del kit sono disponibili anche separatamente

N° Catalogo
Descrizione
SDS

  • RABELADBELISA 5X Assay/Sample Diluent Buffer B (Item E1)SDS

  • RABELADCELISA 1X Assay/Sample Diluent Buffer C (Item L)SDS

  • RABSTOP3ELISA Stop Solution (Item I)SDS

  • RABTMB3ELISA Colorimetric TMB Reagent (HRP Substrate, Item H)SDS

  • RABWASH420X Wash Buffer (Item B)SDS

Pittogrammi

Corrosion

Avvertenze

Warning

Indicazioni di pericolo

Consigli di prudenza

Classi di pericolo

Met. Corr. 1

Codice della classe di stoccaggio

8A - Combustible corrosive hazardous materials


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Role of extracellular molecular chaperones in the folding of oxidized proteins refolding of colloidal thyroglobulin by protein disulfide isomerase and immunoglobulin heavy chain-binding protein.
Delom F, et al.
The Journal of Biological Chemistry, 276(24), 21337-21342 (2001)
A nonsense mutation causes human hereditary congenital goiter with preferential production of a 171-nucleotide-deleted thyroglobulin ribonucleic acid messenger.
Targovnik H M, et al.
The Journal of Clinical Endocrinology and Metabolism, 77(1), 210-215 (1993)
Kathleen M Aicher et al.
PloS one, 14(2), e0212638-e0212638 (2019-02-28)
Gallbladder mucocele formation is an emerging disease in dogs characterized by increased secretion of condensed granules of gel-forming mucin by the gallbladder epithelium and formation of an abnormally thick mucus that can culminate in obstruction of the bile duct or
Serum thyroglobulin and iodine-131 whole-body scan in the diagnosis and assessment of treatment for metastatic differentiated thyroid carcinoma.
Lubin E, et al.
Journal of Nuclear Medicine, 35(2), 257-262 (1994)
Yuwei Wang et al.
Ecotoxicology and environmental safety, 174, 224-235 (2019-03-08)
In recent years, decabromodiphenyl ethane (DBDPE), a new alternative flame retardant to the decabrominated diphenyl ethers (BDE-209), is widely used in a variety of products. Previous studies have indicated that DBDPE, like BDE-209, could disrupt thyroid function. However, compared with

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