528175

Plasminogen, Human Plasma

• Sinonimo/i: Plasminogen, Human Plasma, Profibrinolysin, Plasma Trypsinogen
• Numero CAS: 9001-91-6
• Numero MDL: MFCD00131922
• Codice UNSPSC: 12352202
• NACRES: NA.25

Proprietà

• Origine biologica: human plasma
• Livello qualitativo: 100
• Saggio: ≥95% (SDS-PAGE)
• Forma fisica: lyophilized
• Attività specifica: ≥120 units/mg protein
• Produttore/marchio commerciale: Calbiochem^®
• Condizioni di stoccaggio: OK to freeze
• Solubilità: water: soluble
• Condizioni di spedizione: ambient
• Temperatura di conservazione: −20°C

Descrizione

Descrizione generale

Native plasminogen from human plasma. Plasminogen is a single chain glycoprotein found in normal plasma at ~12 mg per deciliter, and is the inactive precursor of the serine protease plasmin.

Native plasminogen from human plasma. Single chain glycoprotein containing 790 amino acid residues. Found in normal plasma at about 12 mg/100 ml. Inactive precursor of the serine protease plasmin. Plasminogen is converted to the active protease by cleavage at Arg⁵⁶⁰.

Attenzione

Toxicity: Irritant (B)

Definizione di unità

One unit is defined as the amount of enzyme that will hydrolyze 1 µmol of N-tosyl-Arg ethyl ester in 30 min at 37°C, pH 8.0.

Stato fisico

Lyophilized from 20 mM Tris-HCl, 2 mM EDTA, pH 7.5.

Nota sulla preparazione

Prepared from plasma that has been shown by certified tests to be negative for HBsAg and for antibodies to HIV and HCV.

Ricostituzione

Following reconstitution, aliquot and freeze (-20°C) for long-term storage or refrigerate (4°C) for short-term storage. Stock solutions are stable for up to 1 week at 4°C or for up to 2 months at -20°C.

Altre note

Sun, Z., et al. 2002. Biochim. Biophys. Acta1596, 182.
Robbins, K.C., et al. 1967. J. Biol. Chem.242, 2333.

Note legali

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

Esclusione di responsabilità

RESEARCH USE ONLY. This product is regulated in France when intended to be used for scientific purposes, including for import and export activities (Article L 1211-1 paragraph 2 of the Public Health Code). The purchaser (i.e. enduser) is required to obtain an import authorization from the France Ministry of Research referred in the Article L1245-5-1 II. of Public Health Code. By ordering this product, you are confirming that you have obtained the proper import authorization.

Informazioni sulla sicurezza

• Codice della classe di stoccaggio: 11 - Combustible Solids
• Classe di pericolosità dell'acqua (WGK): WGK 3