This product is lyophilized from a solution containing sodium glutamate and human serum albumin. The material may be reconstituted in water. For assay purposes, this material is reconstituted in 10 mM Tris-HCl / 0.1 M NaCl / 0.1% BSA, pH 7.4 . The solution stability has not been determined.
S3134
Streptokinase from β-hemolytic Streptococcus (Lancefield Group C)
lyophilized powder, ≥2,000 units/mg solid
Sinonimo/i:
Streptokinase from Streptococcus hemolyticus
Autenticatiper visualizzare i prezzi riservati alla tua organizzazione & contrattuali
Scegli un formato
10000 UNITS
CHF 67.10
50000 UNITS
CHF 216.00
250000 UNITS
CHF 667.00
CHF 67.10
Spedizione prevista il26 maggio 2025
Scegli un formato
Cambia visualizzazione
10000 UNITS
CHF 67.10
50000 UNITS
CHF 216.00
250000 UNITS
CHF 667.00
About This Item
CHF 67.10
Spedizione prevista il26 maggio 2025
Prodotti consigliati
Stato
lyophilized powder
Attività specifica
≥2,000 units/mg solid
Condizioni di spedizione
wet ice
Temperatura di conservazione
−20°C
Stringa SMILE
N1C(CC(C1)C2CCCCC2)C(=O)O
InChI
1S/C11H19NO2/c13-11(14)10-6-9(7-12-10)8-4-2-1-3-5-8/h8-10,12H,1-7H2,(H,13,14)
XRZWVSXEDRYQGC-UHFFFAOYSA-N
Cerchi prodotti simili? Visita Guida al confronto tra prodotti
Descrizione generale
Research area: Cell signaling
Streptokinase is an extracellular enzyme produced by β-hemolytic Streptococcus. It is a single-chain polypeptide enzyme that consists of multiple structural domains, including α-, β-, and γ-domains.[1]
Streptokinase is an extracellular enzyme produced by β-hemolytic Streptococcus. It is a single-chain polypeptide enzyme that consists of multiple structural domains, including α-, β-, and γ-domains.[1]
Applicazioni
Streptokinase has been used in a study to compare primary coronary intervention and thrombolytic therapy in myocardial infarction patients. [2]
Streptokinase is commonly used as a thrombolytic agent in the therapy of ischemic stroke. This therapy carries the important risk of intracerebral hemorrhage. Streptokinase is also used in the treatment of complicated parapneumonic effusions and empyema where adverse reactions, allergic type, are rare.
Azioni biochim/fisiol
Streptokinase is a potent plasminogen activator. Unlike human proteins tissue plasminogen activator (tPA) and urokinase plasminogen activator (uPA), microbial streptokinase does not directly activate plasminogen. Instead, it activates plasminogen by fibrin-dependent and fibrin-independent. mechanisms.[1] Streptokinase is effective in thrombolytic therapy.[1] While streptokinase offers promising potential in treating ischemic stroke, its use also presents a significant risk of intracerebral hemorrhage. Streptokinase is also used in treating complicated parapneumonic effusions and empyema where allergic reactions, are rare.[3]
Definizione di unità
One unit is equal to the amount of activity in one unit from a Streptokinase International Standard reference vial.
Stato fisico
Lyophilized powder containing ~50% total protein by biuret and sodium glutamate. Total protein composed of enzyme protein and human serum albumin.
Codice della classe di stoccaggio
11 - Combustible Solids
Classe di pericolosità dell'acqua (WGK)
WGK 3
Punto d’infiammabilità (°F)
Not applicable
Punto d’infiammabilità (°C)
Not applicable
Scegli una delle versioni più recenti:
Certificati d'analisi (COA)
Lot/Batch Number
Non trovi la versione di tuo interesse?
Se hai bisogno di una versione specifica, puoi cercare il certificato tramite il numero di lotto.
Possiedi già questo prodotto?
I documenti relativi ai prodotti acquistati recentemente sono disponibili nell’Archivio dei documenti.
I clienti hanno visto anche
Streptokinase--a clinically useful thrombolytic agent
Banerjee A, et al.
Biotechnology Advances, 22(4), 2004-2004 (2004)
Staphylokinase, a fibrin-specific plasminogen activator with therapeutic potential?
D Collen et al.
Blood, 84(3), 680-686 (1994-08-01)
Streptokinase--a clinically useful thrombolytic agent
Banerjee A, et al.
Biotechnology Advances, 22(4), 287-307 (2004)
Effects of plasminogen and streptokinase on the vital functions of nervous tissue cells in culture
Nikandrov, V., et al.
Biomeditsinskaia Khimiia, 54, 192-200 (2012)
Ansar S Zhalyalov et al.
PloS one, 12(7), e0180668-e0180668 (2017-07-08)
Fibrinolysis is a cascade of proteolytic reactions occurring in blood and soft tissues, which functions to disintegrate fibrin clots when they are no more needed. In order to elucidate its regulation in space and time, fibrinolysis was investigated using an
-
how to reconstitute
1 answer-
Helpful?
-
Active Filters
Il team dei nostri ricercatori vanta grande esperienza in tutte le aree della ricerca quali Life Science, scienza dei materiali, sintesi chimica, cromatografia, discipline analitiche, ecc..
Contatta l'Assistenza Tecnica.
