B-024

Butabarbital solution

1.0 mg/mL in methanol, ampule of 1 mL, certified reference material, Cerilliant^®

• Formula empirica (notazione di Hill): C₁₀H₁₆N₂O₃
• Numero CAS: 125-40-6
• Peso molecolare: 212.25
• Numero MDL: MFCD00057560
• Codice UNSPSC: 41116107
• ID PubChem: 329773103
• NACRES: NA.24

Proprietà

• Grado: certified reference material
• Livello qualitativo: 300
• Stato: liquid
• Caratteristiche: SNAP-N-SPIKE^®, SNAP-N-SHOOT^®
• Confezionamento: ampule of 1 mL
• Produttore/marchio commerciale: Cerilliant^®
• drug control: Narcotic Licence Schedule B (Switzerland); psicótropo (Spain); Decreto Lei 15/93: Tabela IV (Portugal)
• Concentrazione: 1.0 mg/mL in methanol
• tecniche: gas chromatography (GC): suitable; liquid chromatography (LC): suitable
• applicazioni: forensics and toxicology
• Formato: single component solution
• Temperatura di conservazione: −20°C
• Stringa SMILE: O=C(NC(C1(CC)C(C)CC)=O)NC1=O
• InChI: 1S/C10H16N2O3/c1-4-6(3)10(5-2)7(13)11-9(15)12-8(10)14/h6H,4-5H2,1-3H3,(H2,11,12,13,14,15); ZRIHAIZYIMGOAB-UHFFFAOYSA-N
• Informazioni sul gene: human ... GABRA1(2554) , GABRA2(2555) , GABRA3(2556) , GABRA4(2557) , GABRA5(2558) , GABRA6(2559) , GABRB1(2560) , GABRB2(2561) , GABRB3(2562) , GABRD(2563) , GABRE(2564) , GABRG1(2565) , GABRG2(2566) , GABRG3(2567) , GABRP(2568) , GABRQ(55879)

Descrizione

Descrizione generale

Butabarbital is a barbiturate prescribed as a sleep aid under the trade name Butisol. sold under the name Butisol as a sleep aid. This analytical reference material is suitable for use in LC/MS or GC/MS applications for clinical toxicology, forensic analysis, or urine drug testing.

Applicazioni

• Propranolol-D7 labeled solution: (±)-Propranolol-D₇ used in the analysis of β-blockers and metabolites in milk powder, employing high-performance liquid chromatography coupled to quadrupole Orbitrap high-resolution mass spectrometry. This application underscores the compound′s utility in sophisticated bioanalytical assessments, crucial for understanding pharmacokinetic behaviors in diverse matrices (Cheng et al., 2019).


• Stable isotope-labeled propranolol for bioanalysis: Propranolol-D₇ used as an internal standard in a simultaneous determination method for propranolol and its metabolite in human plasma. The method, utilizing solid phase extraction and liquid chromatography/electrospray tandem mass spectrometry, highlights the role of stable isotopes in enhancing the precision and reliability of pharmacokinetic studies (Partani et al., 2009).


• Propranolol-D₇ tracer for pharmacokinetic studies: (±)-Propranolol-D₇ employed in an innovative technique combining laser microdissection and liquid vortex capture-mass spectrometry for absolute quantitation of propranolol in thin tissue sections. This method allows for precise measurement of drug distribution in small, spatially distinct regions, enhancing the understanding of drug dynamics within organs (Cahill et al., 2016).

Note legali

CERILLIANT is a registered trademark of Merck KGaA, Darmstadt, Germany

Snap-N-Shoot is a registered trademark of Cerilliant Corporation

Snap-N-Spike is a registered trademark of Merck KGaA, Darmstadt, Germany

Informazioni sulla sicurezza

• Pittogrammi: GHS02,GHS06,GHS08
• Avvertenze: Danger
• Indicazioni di pericolo: H225,H301 + H311 + H331,H370
• Consigli di prudenza: P210 - P233 - P280 - P301 + P310 - P303 + P361 + P353 - P304 + P340 + P311
• Classi di pericolo: Acute Tox. 3 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Flam. Liq. 2 - STOT SE 1
• Organi bersaglio: Eyes
• Codice della classe di stoccaggio: 3 - Flammable liquids
• Classe di pericolosità dell'acqua (WGK): WGK 2
• Punto d’infiammabilità (°F): 49.5 °F - closed cup
• Punto d’infiammabilità (°C): 9.7 °C - closed cup