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810110P

Avanti

12-NBD Stearate

Avanti Research - A Croda Brand 810110P, powder

Sinonimo/i:

12-N-methyl-(7-nitrobenz-2-oxa-1,3-diazo)aminostearic acid

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1 MG
CHF 236.00

CHF 236.00


Spedizione prevista il13 aprile 2025


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Cambia visualizzazione
1 MG
CHF 236.00

About This Item

Formula empirica (notazione di Hill):
C25H40N4O5
Numero CAS:
Peso molecolare:
476.61
Numero MDL:
Codice UNSPSC:
12352211
NACRES:
NA.25

CHF 236.00


Spedizione prevista il13 aprile 2025


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Saggio

>99% (TLC)

Stato

powder

Confezionamento

pkg of 1 × 1 mg (810110P-1mg)

Produttore/marchio commerciale

Avanti Research - A Croda Brand 810110P

Condizioni di spedizione

dry ice

Temperatura di conservazione

−20°C

Stringa SMILE

[N+](=O)([O-])c1c2n[o]nc2c(cc1)N(C(CCCCCCCCCCC(=O)O)CCCCCC)C

InChI

1S/C25H40N4O5/c1-3-4-5-12-15-20(16-13-10-8-6-7-9-11-14-17-23(30)31)28(2)21-18-19-22(29(32)33)25-24(21)26-34-27-25/h18-20H,3-17H2,1-2H3,(H,30,31)
SAAVELCIPHKGJE-UHFFFAOYSA-N

Descrizione generale

12-NBD Stearate is amphipathic, nonesterifiable fluorescent fatty acid probe[1] and is a long-chain fatty acid (LCFA) derivative.[2]

Applicazioni

12-NBD Stearate has been used in the fluorescent labeling of omega-3 fatty acid in biomaterial films[3] and as a ligand for fatty acid binding protein 5 (FABP5) in competitive binding based high throughput fluorescence displacement assay.[4] It may be used a ligand fluorescence displacement assay of fatty-acid binding protein 5 (FABP5).[5]

Azioni biochim/fisiol

12-NBD Stearate incorporated in lipid droplets[1] and is used majorly in fluorescence displacement binding studies of fatty-acid binding proteins.[6] The sterol carrier protein-2 (SCP-2) 15-kDa isoform favours NBD Stearate transport.[1] The uptake of NBD Stearate is regulated by fatty acid binding protein (FABP) expression regulates uptake[7] and inhibited by filipin III.[2]

Confezionamento

5 mL Amber Glass Screw Cap Vial (810110P-1mg)

Note legali

Avanti Research is a trademark of Avanti Polar Lipids, LLC

Codice della classe di stoccaggio

11 - Combustible Solids


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Prostate cancer (PCa) is defined by dysregulated lipid signaling and is characterized by upregulation of lipid metabolism-related genes including fatty acid binding protein 5 (FABP5), fatty acid synthase (FASN), and monoacylglycerol lipase (MAGL). FASN and MAGL are enzymes that generate
E J Murphy
The American journal of physiology, 275(2 Pt 1), G237-G243 (1998-08-04)
The effects of sterol carrier protein-2 (SCP-2) expression on fatty acid uptake and cytoplasmic diffusion were determined using L cell fibroblasts transfected with cDNA encoding either the 15- or 13. 2-kDa form of SCP-2. Cis-parinarate and 12-N-methyl-(7-nitrobenz-2-oxa-1,3-diazol)aminostearate (NBD-stearate) were used

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