790427C

06:0 PC-d22

Avanti Research^™ - A Croda Brand 790427C

• Sinonimo/i: 1,2-dihexanoyl-d22-sn-glycero-3-phosphocholine
• Formula empirica (notazione di Hill): C₂₀H₁₈NO₈PD₂₂
• Numero CAS: 328946-18-5
• Peso molecolare: 475.64
• Numero MDL: MFCD00003646
• Codice UNSPSC: 12352211
• NACRES: NA.12

Proprietà

• Saggio: >99% (TLC)
• Stato: liquid
• Confezionamento: pkg of 1 × 1 mL (790427C-10mg)
• Produttore/marchio commerciale: Avanti Research^™ - A Croda Brand 790427C
• Concentrazione: 10 mg/mL (790427C-10mg)
• Condizioni di spedizione: dry ice
• Temperatura di conservazione: −20°C

Descrizione

Descrizione generale

Deuterated fatty acids experience exchange of the deuteriums on the alpha carbon to the carbonyl, i.e., C2 position, and will therefore be a mixture of compounds that are fully deuterated and partially deuterated at that position.

Phosphatidylcholine is a zwitterionic glycerophospholipid, containing choline.[1] It consists of a head and two tails. Head group contains choline and phosphate. Head is polar and water soluble. The tail group contains two fatty acyl chains esterified with glycerol. Tail group is non-polar and water-insoluble.[2] Phosphatidylcholine is synthesized in the liver by phosphatidylethanolamine methyltransferase (PEMT) pathway. It is also synthesized by the Kennedy pathway and the Lands cycle.[3]

Applicazioni

06:0 PC-d22 (1,2-dihexanoyl-d22-sn-glycero-3-phosphocholine) has been used:

• as bicelles for lipid in HN-HN nuclear overhauser enhancement (NOE) detection[4]
• as an internal standard in residual algal suspension for liquid chromatography-mass spectrometry analysis (LC-MS/MS)[5]
• to produce bicelles to investigate C-peptide and membrane interaction by diffusion nuclear magnetic resonance (NMR) and 2D total correlation spectroscopy (TOCSY)[6]

Azioni biochim/fisiol

Phosphatidylcholine (PC) is a major component of the membrane bilayer. It is involved in the synthesis of signaling molecules. PC is the precursor for the synthesis of sphingomyelin and phosphatidylserine.[1]

Confezionamento

5 mL Clear Glass Sealed Ampule (790427C-10mg)

Note legali

Avanti Research is a trademark of Avanti Polar Lipids, LLC

Informazioni sulla sicurezza

• Pittogrammi: GHS06,GHS08
• Avvertenze: Danger
• Indicazioni di pericolo: H302,H315,H319,H331,H336,H351,H361d,H372
• Consigli di prudenza: P260 - P280 - P301 + P312 + P330 - P304 + P340 + P311 - P305 + P351 + P338 - P403 + P233
• Classi di pericolo: Acute Tox. 3 Inhalation - Acute Tox. 4 Oral - Carc. 2 - Eye Irrit. 2 - Repr. 2 - Skin Irrit. 2 - STOT RE 1 - STOT SE 3
• Organi bersaglio: Central nervous system
• Classe di pericolosità dell'acqua (WGK): WGK 3