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901609

Sigma-Aldrich

Diisopropylcarbodiimide solution

1 M in dichloromethane

Sinonimo/i:

Diisopropylmethanediimine

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About This Item

Formula condensata:
C7H14N2
Numero CAS:
Numero MDL:
Codice UNSPSC:
12352200

Forma fisica

liquid

Impiego in reazioni chimiche

reaction type: Coupling Reactions

Concentrazione

1 M in dichloromethane

Indice di rifrazione

n/D 1.4251

Densità

1.2231

applicazioni

peptide synthesis

InChI

1S/C7H14N2/c1-6(2)8-5-9-7(3)4/h6-7H,1-4H3
BDNKZNFMNDZQMI-UHFFFAOYSA-N

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Descrizione generale

DIC is an abbreviated form of N,N′-diisopropylcarbodiimide. It plays a role in the cyclization of N-(β-hydroxy)amides to form 2-oxazolines.

Applicazioni

  • Alternative to dicyclohexylcarbodiimide in peptide synthesis.
  • Coupling reagent for peptide syntheses.
  • DIC (N,N′-Diisopropylcarbodiimide) has been used in combination with 1-hydroxy-7-azabenzotriazole (HOAt) for the coupling of amino acid with N-allylglycine to form N-allylpeptide.
Valuable reagent offered as a solution in dichloromethane for more convenient handling.

Prodotti correlati

N° Catalogo
Descrizione
Determinazione del prezzo

Avvertenze

Danger

Classi di pericolo

Acute Tox. 2 Inhalation - Carc. 2 - Eye Dam. 1 - Flam. Liq. 3 - Resp. Sens. 1 - Skin Irrit. 2 - Skin Sens. 1 - STOT SE 3

Organi bersaglio

Central nervous system

Codice della classe di stoccaggio

3 - Flammable liquids

Classe di pericolosità dell'acqua (WGK)

WGK 3

Punto d’infiammabilità (°F)

91.4 °F

Punto d’infiammabilità (°C)

33 °C


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