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900148

Sigma-Aldrich

Iron oxide (II,III), nanoparticles

30 nm avg. part. size (TEM), streptavidin functionalized, 1 mg/mL in H2O

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About This Item

Codice UNSPSC:
12352303
NACRES:
NA.23

Forma fisica

dispersion
nanoparticles

Livello qualitativo

Confezionamento

pkg of 1 mL

Condizioni di stoccaggio

do not freeze

Concentrazione

1 mg/mL in H2O

Dimens. media delle particelle

30 nm (TEM)

Gruppo funzionale

streptavidin

Temperatura di conservazione

2-8°C

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Descrizione generale

Recent docking studies highlight the potential interaction of iron oxide (II,III) nanoparticles (IONPs) with the SARS-CoV-2 spike protein receptor binding domain. This may target viral entry in host cells and also render virions inactive.

Applicazioni

IONPs may be used in the nanoparticle preparation for evaluation of their antiviral property against H1N1 influenza A virus.
Iron oxide nanoparticles exhibit biocompatibility and non-toxicity and are used as magnetic resonance imaging contrast agents, gene carriers for gene therapy, therapeutic agents for hyperthermia-based cancer treatment, magnetic sensing probes for in vivo diagnostics and for target specific drug delivery.

Note legali

Product of Ocean Nanotech, LLC.

Codice della classe di stoccaggio

12 - Non Combustible Liquids

Classe di pericolosità dell'acqua (WGK)

WGK 2

Punto d’infiammabilità (°F)

Not applicable

Punto d’infiammabilità (°C)

Not applicable


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A Molecular Docking Study Repurposes FDA Approved Iron Oxide Nanoparticles to Treat and Control COVID-19 Infection
Abo-Zeid Y, et al.
European Journal of Pharmaceutical Sciences, 105465-105465 (2020)
Iron oxide nanoparticles based antiviral activity of H1N1 influenza A virus
Kumar R, et al.
Journal of Infection and Chemotherapy, 25(5), 325-329 (2019)
Joan Estelrich et al.
International journal of molecular sciences, 16(4), 8070-8101 (2015-04-14)
In this review, we discuss the recent advances in and problems with the use of magnetically-guided and magnetically-responsive nanoparticles in drug delivery and magnetofection. In magnetically-guided nanoparticles, a constant external magnetic field is used to transport magnetic nanoparticles loaded with
Xianglong Hu et al.
Dalton transactions (Cambridge, England : 2003), 44(9), 3904-3922 (2015-01-13)
Responsive polymeric assemblies and hybrid superstructures fabricated from stimuli-sensitive polymers and inorganic nanoparticles (NPs) have been the subject of extensive investigations during the past few decades due to their distinct advantages such as an improved water solubility, stimuli-responsiveness, excellent biocompatibility
Jin Xie et al.
Theranostics, 2, 122-124 (2012-01-31)
This theme issue provides a timely collection of studies on magnetic nanoparticle-based imaging, bio-sensing, therapy and/or their combinations.

Articoli

Professor Hui Mao explores the use of superparamagnetic iron oxide nanoparticles (INOPs) that offer an alternate contrast-enhancing mechanism.

Prof. Yadong Yin discusses various synthesis methods of magnetite nanocrystals and their applications in different fields.

Il team dei nostri ricercatori vanta grande esperienza in tutte le aree della ricerca quali Life Science, scienza dei materiali, sintesi chimica, cromatografia, discipline analitiche, ecc..

Contatta l'Assistenza Tecnica.