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765260

Sigma-Aldrich

Gold nanoparticles

5 nm diameter, amine functionalized, PEG 3000 coated, OD 50, dispersion in H2O

Sinonimo/i:

Gold nanoparticles NH2 functionalized, Au NP NH2, Gold Colloid

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About This Item

Codice UNSPSC:
12162002
NACRES:
NA.23

Materiali

PEG 3000

Forma fisica

dispersion in H2O
nanoparticles

Confezionamento

glass bottle of 1 mL

OD

50

Diametro

5 nm

pH

6.0-8.0 (25 °C)

Solubilità

water: miscible

Densità

1.00 g/cm3

λmax

515 nm

Gruppo funzionale

amine

Temperatura di conservazione

2-8°C

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Applicazioni

Amine functionalized, PEG 3000 coated, OD 50, and H2O dispersed gold nanoparticles (5 nm) can be used in the activation of silica nanosphere for the decomposition of formic acid. They may be used in the radiosensitization and imaging of cancer cells.
AuNPs can be potentially immobilized on antibodies to improve the sensitivity of optical fiber sensors for the screening of COVID-19. They can also be deposited on the titanium electrode for the formation of a miniaturized device for the electrochemical detection of DNA hybridization, which can be used in the diagnosis of COVID-19.
Functionalized particles have been extensively used to study cellular uptake of nanoparticles and targeted drug delivery.

Caratteristiche e vantaggi

  • Negatively charged siRNA-PEG complex which is attached to positively charged GNPs is easily cleavable in reductive cytosolic environment thus enabling the release of siRNA into cytosol.
  • Decreases the cytotoxicity and increases efficiency of GNPs. PEG increases the stability of the nanoparticles and prevents agglomeration.

Codice della classe di stoccaggio

12 - Non Combustible Liquids

Classe di pericolosità dell'acqua (WGK)

WGK 1

Punto d’infiammabilità (°F)

Not applicable

Punto d’infiammabilità (°C)

Not applicable

Certificati d'analisi (COA)

Cerca il Certificati d'analisi (COA) digitando il numero di lotto/batch corrispondente. I numeri di lotto o di batch sono stampati sull'etichetta dei prodotti dopo la parola ‘Lotto’ o ‘Batch’.

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Gold nanoparticles

Gold nanoparticles for radiosensitizing and imaging of cancer cells
Borran AA, et al.
Radiation Physics and Chemistry, 152(25), 137-144 (2018)
Strong metal-molecular support interaction (SMMSI): amine-functionalized gold nanoparticles encapsulated in silica nanospheres highly active for catalytic decomposition of formic acid
Yadav M, et al.
Journal of Materials Chemistry, 22(25), 12582-12586 (2012)
Optical Fiber Sensors for Rapid Screening of COVID-19
Nag P, et al.
Transactions of the Indian National Academy of Engineering, 152(25), 1-4 (2020)
Scott H Brewer et al.
Langmuir : the ACS journal of surfaces and colloids, 21(20), 9303-9307 (2005-09-21)
The interaction of bovine serum albumin (BSA) with gold colloids and surfaces was studied using zeta-potential and quartz crystal microbalance (QCM) measurements, respectively, to determine the surface charge and coverage. The combination of these two measurements suggests that BSA binding
Functionalized gold nanoparticles and their biomedical applications
Tiwari, P. M., Vig, K., Dennis, V. A., & Singh, S. R.
Nanomaterials, 1(1), 31-63 (2011)

Articoli

Magnetic Nanoparticles for Cancer Theranostics

The recent emergence of a number of highly functional nanomaterials has enabled new approaches to the understanding, diagnosis, and treatment of cancer.

Micro- and Nanofabricated Biomaterials

Biomaterials science integrates smart materials into biological research, requiring a deep understanding of biological systems.

Il team dei nostri ricercatori vanta grande esperienza in tutte le aree della ricerca quali Life Science, scienza dei materiali, sintesi chimica, cromatografia, discipline analitiche, ecc..

Contatta l'Assistenza Tecnica.