682144

(R)-(–)-4,12-Bis(diphenylphosphino)-[2.2]-paracyclophane

96%

• Sinonimo/i: (R)-Phanephos
• Formula empirica (notazione di Hill): C₄₀H₃₄P₂
• Numero CAS: 364732-88-7
• Peso molecolare: 576.65
• Numero MDL: MFCD03094575
• Codice UNSPSC: 12352002
• ID PubChem: 24885681
• NACRES: NA.22

Proprietà

• Saggio: 96%
• Stato: solid
• Attività ottica: [α]/D -34±4°, c = 1 in chloroform
• Punto di fusione: 222-226 °C
• Gruppo funzionale: phosphine
• Stringa SMILE: P(c7ccccc7)(c6ccccc6)c1c2ccc(c1)CCc3c(cc(cc3)CC2)P(c5ccccc5)c4ccccc4
• InChI: 1S/C40H34P2/c1-5-13-35(14-6-1)41(36-15-7-2-8-16-36)39-29-31-21-25-33(39)27-23-32-22-26-34(28-24-31)40(30-32)42(37-17-9-3-10-18-37)38-19-11-4-12-20-38/h1-22,25-26,29-30H,23-24,27-28H2; GYZZZILPVUYAFJ-UHFFFAOYSA-N

Descrizione

Applicazioni

(R)-(-)-4,12-Bis(diphenylphosphino)-[2.2]-paracyclophane may be used as a ligand in the following processes:

• Enantioselective reductive cyclization of 1,6-enynes via asymmetric hydrogenation in the presence of a rhodium catalyst to form alkylidene-substituted heterocycles.[1]
• Asymmetric hydroboration of 3,3-disubstituted cyclopropenes to form 2,2-disubstituted cyclopropyl boronates.[2]
• Asymmetric ring-opening reactions of azabenzonorbornadienes in the presence of zinc(II) triflate and palladium(II) acetate to form aminodihydronaphthalenes.[3]

Efficient ligand for asymmetric hydrogentation of dehydroamino acids, methyl esters and keytones.[4][5]

Note legali

Sold in collaboration with Johnson Matthey Catalyst for research purposes only. US5874629 and any patents arising therefrom apply.

Informazioni sulla sicurezza

• Codice della classe di stoccaggio: 11 - Combustible Solids
• Classe di pericolosità dell'acqua (WGK): WGK 3
• Punto d’infiammabilità (°F): Not applicable
• Punto d’infiammabilità (°C): Not applicable
• Dispositivi di protezione individuale: dust mask type N95 (US), Eyeshields, Gloves