362433

Diethyl (N-methoxy-N-methylcarbamoylmethyl)phosphonate

96%

• Sinonimo/i: N-Methoxy-N-methyl-2-(diethyl phosphono)acetamide, N-Methoxy-N-methyl-phosphonoacetamide diethyl ester, Diethyl N-methoxy-N-methylphosphonoacetamide, Diethylphosphonoacetic acid N-methyl-N-methoxyamide
• Formula condensata: CH₃ON(CH₃)COCH₂P(O)(OC₂H₅)₂
• Numero CAS: 124931-12-0
• Peso molecolare: 239.21
• Beilstein: 1875865
• Numero MDL: MFCD00134233
• Codice UNSPSC: 12352108
• ID PubChem: 24862312
• NACRES: NA.22

Proprietà

• Saggio: 96%
• Forma fisica: liquid
• Impiego in reazioni chimiche: reaction type: C-C Bond Formation
• Indice di rifrazione: n20/D 1.455 (lit.)
• P. eboll.: 90 °C/17 mmHg (lit.)
• Densità: 1.163 g/mL at 25 °C (lit.)
• Gruppo funzionale: amine; phosphonate
• Stringa SMILE: CCOP(=O)(CC(=O)N(C)OC)OCC
• InChI: 1S/C8H18NO5P/c1-5-13-15(11,14-6-2)7-8(10)9(3)12-4/h5-7H2,1-4H3; WYLRYBDGIILFIR-UHFFFAOYSA-N

Descrizione

Applicazioni

Reactant for:

• Preparation of ring-expanded bryostatin analogs as antitumor agents
• Asymmertic synthesis of pinnatoxins A and G via diastereoselective Ireland-Claisen rearrangement, ring closing metathesis, and cyclization
• Rh2(II)-catalyzed nitro-group migration reactions
• Stereoselective synthesis of cyclohexanones via phase transfer catalyzed double addition reactions
• Stereoselective synthesis of (+)-polyrhacitide A via aldol reaction, Horner-Wardsworth-Emmons reaction, Evans acetal intramolecular oxa-Michael reaction and diastereoselective syn reduction reaction as the key steps
• Preparation of substituted furans via olefin cross-metathesis

Wittig carbonylating reagent.

Informazioni sulla sicurezza

• Pittogrammi: GHS07
• Avvertenze: Warning
• Indicazioni di pericolo: H315,H319,H335
• Consigli di prudenza: P261 - P264 - P271 - P280 - P302 + P352 - P305 + P351 + P338
• Classi di pericolo: Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
• Organi bersaglio: Respiratory system
• Codice della classe di stoccaggio: 10 - Combustible liquids
• Classe di pericolosità dell'acqua (WGK): WGK 3
• Punto d’infiammabilità (°F): 230.0 °F - closed cup
• Punto d’infiammabilità (°C): 110 °C - closed cup
• Dispositivi di protezione individuale: Eyeshields, Gloves, type ABEK (EN14387) respirator filter