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246379

Sigma-Aldrich

Azelaic acid

98%

Sinonimo/i:

Nonanedioic acid

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CHF 113.00
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CHF 173.00

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25 G
CHF 113.00
100 G
CHF 173.00

About This Item

Formula condensata:
HO2C(CH2)7CO2H
Numero CAS:
123-99-9
Peso molecolare:
188.22
Beilstein:
1101094
Numero CE:
204-669-1
Numero MDL:
MFCD00004432
Codice UNSPSC:
12162002
ID PubChem:
24278221
NACRES:
NA.23

CHF 113.00

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Densità del vapore

6.5 (vs air)

Tensione di vapore

<1 mmHg ( 20 °C)

Saggio

98%

Stato

powder

P. ebollizione

286 °C/100 mmHg (lit.)

Punto di fusione

109-111 °C (lit.)

Stringa SMILE

OC(=O)CCCCCCCC(O)=O

InChI

1S/C9H16O4/c10-8(11)6-4-2-1-3-5-7-9(12)13/h1-7H2,(H,10,11)(H,12,13)
BDJRBEYXGGNYIS-UHFFFAOYSA-N

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Descrizione generale

Azelaic acid is an important monomer in the synthesis of various polymers. The presence of two carboxylic acid groups enables azelaic acid to act as a monomer for polycondensation reactions, leading to the formation of polyesters and other polymeric materials. Additionally, it is also used to prepare azelaic acid-based plasticizers to improve the mechanical properties of PVC, making them suitable for various applications, including films, coatings, and flexible products.[1][2][3]

Applicazioni

Azelaic acid can be used:
  • As a bio-based monomer in the development of biodegradable polymers. These polymers are explored for a range of applications, including packaging materials, agricultural films, and other products where biodegradability is a key requirement.
  • As a crucial component in the synthesis of biodegradable copolyester plasticizers for PVC applications.
  • As a monomer in the synthesizing poly(glycerol azelaic acid) for tissue engineering applications. Its contributions to biocompatibility, mechanical properties, degradation behavior, and hydrophilicity make it an essential building block for developing advanced biomaterials aimed at enhancing tissue regeneration processes. In drug delivery systems, azelaic acid may play a role in the synthesis of polymers or other compounds used in drug delivery, potentially enhancing medication effectiveness through improved solubility or stability.
  • In skincare products.

Pittogrammi

Exclamation mark
GHS07

Avvertenze

Warning

Indicazioni di pericolo

H315,H319

Classi di pericolo

Eye Irrit. 2 - Skin Irrit. 2

Codice della classe di stoccaggio

11 - Combustible Solids

Classe di pericolosità dell'acqua (WGK)

WGK 1

Punto d’infiammabilità (°F)

410.0 °F - closed cup

Punto d’infiammabilità (°C)

210 °C - closed cup

Dispositivi di protezione individuale

Eyeshields, Gloves, type N95 (US)

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Certificati d'analisi (COA)

Lot/Batch Number
WXBF0140V
WXBF1830V
WXBF1605V
WXBD6695V
WXBD1400V

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Seyed Dariush Taherzade et al.
Nanomaterials (Basel, Switzerland), 10(12) (2020-12-02)
Combined therapies emerge as an interesting tool to overcome limitations of traditional pharmacological treatments (efficiency, side effects). Among other materials, metal-organic frameworks (MOFs) offer versatilities for the accommodation of multiple and complementary active pharmaceutical ingredients (APIs): accessible large porosity, availability
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Excess cathelicidin and kallikrein 5 (KLK5) have been hypothesized to play a role in the pathophysiology of rosacea. We sought to evaluate the effects of azelaic acid (AzA) on these elements of the innate immune system. Gene expression and protease
Chaemyeong Lee et al.
Scientific reports, 7(1), 13797-13797 (2017-10-25)
Inspired by adhesive mussel proteins, nanospherical self-assemblies were prepared from bolaamphiphiles containing 3,4-dihydroxyphenylalanine (DOPA) moieties, and a suspension of the bolaamphiphile assemblies was used for the preparation of a patterned surface that enhanced cell adhesion and viability. The abundant surface-exposed
Esther J van Zuuren et al.
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Maria Zoeller et al.
Plant physiology, 160(1), 365-378 (2012-07-24)
Lipid peroxidation (LPO) is induced by a variety of abiotic and biotic stresses. Although LPO is involved in diverse signaling processes, little is known about the oxidation mechanisms and major lipid targets. A systematic lipidomics analysis of LPO in the
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Questions

1–2 of 2 Questions  

  1. How can I determine the shelf life / expiration / retest date of this product?

    1 answer

    1. If this product has an expiration or retest date, it will be shown on the Certificate of Analysis (COA, CofA). If there is no retest or expiration date listed on the product's COA, we do not have suitable stability data to determine a shelf life. For these products, the only date on the COA will be the release date; a retest, expiration, or use-by-date will not be displayed.
      For all products, we recommend handling per defined conditions as printed in our product literature and website product descriptions. We recommend that products should be routinely inspected by customers to ensure they perform as expected.
      For products without retest or expiration dates, our standard warranty of 1 year from the date of shipment is applicable.
      For more information, please refer to the Product Dating Information document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/449/386/product-dating-information-mk.pdf

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  2. How is shipping temperature determined? And how is it related to the product storage temperature?

    1 answer

    1. Products may be shipped at a different temperature than the recommended long-term storage temperature. If the product quality is sensitive to short-term exposure to conditions other than the recommended long-term storage, it will be shipped on wet or dry-ice. If the product quality is NOT affected by short-term exposure to conditions other than the recommended long-term storage, it will be shipped at ambient temperature. As shipping routes are configured for minimum transit times, shipping at ambient temperature helps control shipping costs for our customers. For more information, please refer to the Storage and Transport Conditions document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/316/622/storage-transport-conditions-mk.pdf

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