208949
2-Fluorophenylacetic acid
98%
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About This Item
Formula condensata:
FC6H4CH2CO2H
Numero CAS:
Peso molecolare:
154.14
Beilstein:
775955
Numero CE:
Numero MDL:
Codice UNSPSC:
12352100
ID PubChem:
NACRES:
NA.22
Prodotti consigliati
Saggio
98%
Forma fisica
solid
Punto di fusione
60-62 °C (lit.)
Stringa SMILE
OC(=O)Cc1ccccc1F
InChI
1S/C8H7FO2/c9-7-4-2-1-3-6(7)5-8(10)11/h1-4H,5H2,(H,10,11)
RPTRFSADOICSSK-UHFFFAOYSA-N
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Descrizione generale
2-Fluorophenylacetic acid is chiral derivatizing agent for determination of enantiomeric composition of chiral, nonracemic compounds by 19F NMR spectroscopy.
Applicazioni
2-Fluorophenylacetic acid was used:
- in the synthesis of thiazolino[3,2-c]pyrimidin-5,7-diones and N-[2-(3,4-dichlorophenyl)-ethyl]-N′-[2-(2-fluorophenyl)-ethyl]-ethane-1,2-diamine
- as chiral derivatizing agent for determination of enantiomeric composition of chiral, nonracemic compounds by 19F NMR spectroscopy
Certificati d'analisi (COA)
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I documenti relativi ai prodotti acquistati recentemente sono disponibili nell’Archivio dei documenti.
Boron trifluoride-induced reactions of phenylglycidyl ethers: a convenient synthesis of enantiopure, stereodefined fluorohydrins.
Islas-Gonzalez G, et al.
Tetrahedron Letters, 45(33), 6337-6341 (2004)
Joseph Pontillo et al.
Bioorganic & medicinal chemistry letters, 15(5), 1407-1411 (2005-02-17)
Treatment of various 2-methyl oxazolines or thiazolines with chlorocarbonyl isocyanate gives the corresponding bicyclic oxazolino- or thiazolino[3,2-c]pyrimidin-5,7-dione derivatives in very good yield. This reaction has been applied to the rapid syntheses of human gonadotropin-releasing hormone (hGnRH) receptor antagonists for SAR
Yaqun Li et al.
The Korean journal of pain, 34(1), 27-34 (2021-01-01)
Chemotherapy-induced peripheral neuropathy (CIPN) is a major reason for stopping or changing anticancer therapy. Among the proposed pathomechanisms underlying CIPN, proinflammatory processes have attracted increasing attention. Here we assessed the role of prostaglandin D2 (PGD2) signaling in cisplatin-induced neuropathic pain.
Jonathan M Fitzsimmons et al.
Medicinal chemistry, 1(102) (2011-12-25)
Eight halogenated
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