146625
Bathocuproinedisulfonic acid disodium salt hydrate
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About This Item
Formula empirica (notazione di Hill):
C26H18N2Na2O6S2 · xH2O
Numero CAS:
Peso molecolare:
564.54 (anhydrous basis)
Numero MDL:
Codice UNSPSC:
12352100
ID PubChem:
NACRES:
NA.22
Prodotti consigliati
Forma fisica
powder
Punto di fusione
300 °C (lit.)
Gruppo funzionale
phenyl
sulfonic acid
Stringa SMILE
O.[Na+].[Na+].Cc1nc2c(ccc3c(-c4ccccc4)c(c(C)nc23)S([O-])(=O)=O)c(-c5ccccc5)c1S([O-])(=O)=O
InChI
1S/C26H20N2O6S2.2Na.H2O/c1-15-25(35(29,30)31)21(17-9-5-3-6-10-17)19-13-14-20-22(18-11-7-4-8-12-18)26(36(32,33)34)16(2)28-24(20)23(19)27-15;;;/h3-14H,1-2H3,(H,29,30,31)(H,32,33,34);;;1H2/q;2*+1;/p-2
ZAGWMJUGRCMNGX-UHFFFAOYSA-L
Descrizione generale
Bathocuproine disulfonic acid (BCDS) is a stable Cu+ chelator and BCDS-Cu+ inhibits the HIV-1 wild type protease as well as a mutant HIV-1 protease lacking cysteine. It is an extracellular copper chelator.
Applicazioni
Bathocuproinedisulfonic acid disodium salt hydrate was used as chelator in electron spin resonance spin trapping technique to study free radical generation in rats with acute sodium formate poisoning. It was used as reagent for determination of Cu and Cu-protein complexes.
Codice della classe di stoccaggio
11 - Combustible Solids
Classe di pericolosità dell'acqua (WGK)
WGK 3
Punto d’infiammabilità (°F)
Not applicable
Punto d’infiammabilità (°C)
Not applicable
Dispositivi di protezione individuale
Eyeshields, Gloves, type N95 (US)
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A E Dikalova et al.
Proceedings of the National Academy of Sciences of the United States of America, 98(24), 13549-13553 (2001-11-22)
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A method of protein determination has been developed which combines the biuret reaction and the copper(I)-bathocuproine chelate reaction. Protein in the specimen forms a Cu(2+)-protein chelate complex (biuret reaction) during the first step. Excess Cu2+ is reduced to Cu+ by
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