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13815

Sigma-Aldrich

1-Benzylpiperazine

≥97.0% (GC)

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About This Item

Formula empirica (notazione di Hill):
C11H16N2
Numero CAS:
2759-28-6
Peso molecolare:
176.26
Beilstein:
141624
Numero CE:
220-423-6
Numero MDL:
MFCD00005967
Codice UNSPSC:
12352100
ID PubChem:
57647104
Prezzi e disponibilità al momento non sono disponibili

Livello qualitativo

100

Saggio

≥97.0% (GC)

Controllo stupefacenti

USDEA Schedule I; regulated under CDSA - not available from Sigma-Aldrich Canada

Indice di rifrazione

n20/D 1.547 (lit.)
n20/D 1.547

Punto di fusione

17-20 °C

Densità

1.014 g/mL at 25 °C (lit.)

Gruppo funzionale

phenyl

Stringa SMILE

C1CN(CCN1)Cc2ccccc2

InChI

1S/C11H16N2/c1-2-4-11(5-3-1)10-13-8-6-12-7-9-13/h1-5,12H,6-10H2
IQXXEPZFOOTTBA-UHFFFAOYSA-N

Informazioni sul gene

rat ... Htr2a(29595) , Htr2c(25187)

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Descrizione generale

1-Benzylpiperazine has stimulant and euphoric properties[1]. It is commonly used constituent of party pill drugs[2]. It is a potential antidepressant and is an active metabolite of the withdrawn antidepressant drug piberaline[3].

Applicazioni

1-Benzylpiperazine was used to study the inhibition of various acetylcholinesterases by 7-ethyl-10-[4-(1-piperidino)-1-piperidino]carbonyloxycamptothecin and related compounds[4].

Altre note

Sales restrictions may apply

Pittogrammi

Corrosion
GHS05

Avvertenze

Danger

Indicazioni di pericolo

H314,H412

Classi di pericolo

Aquatic Chronic 3 - Eye Dam. 1 - Skin Corr. 1B

Codice della classe di stoccaggio

8A - Combustible corrosive hazardous materials

Classe di pericolosità dell'acqua (WGK)

WGK 3

Punto d’infiammabilità (°F)

253.4 °F - closed cup

Punto d’infiammabilità (°C)

123 °C - closed cup

Dispositivi di protezione individuale

Faceshields, Gloves, Goggles, type ABEK (EN14387) respirator filter

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Certificati d'analisi (COA)

Lot/Batch Number
BCBK7041V
013099/1
352349/1
043423/1
011970/1

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Simon Elliott et al.
Journal of analytical toxicology, 32(2), 172-177 (2008-03-13)
Piperazines such as 1-benzylpiperazine (BZP), 1-(3-trifluromethylphenyl)piperazine (3-TFMPP), and 1-(3-chlorophenyl)piperazine (3-CPP) have become recent drugs of abuse. With stimulant effects comparable to amphetamines but with a lower potency and differential global scheduling status, they have been sold as a supposed legal
Márcia Sá Monteiro et al.
Archives of toxicology, 87(6), 929-947 (2013-05-21)
N-benzylpiperazine (BZP) has become popular among recreational drug users as the major active ingredient of "party pills" due to its stimulant and euphoric properties. Before BZP legal restrictions, these pills were sold as a safe and legal alternative to classical
Paul Gee et al.
Clinical toxicology (Philadelphia, Pa.), 48(3), 230-233 (2010-02-27)
1-benzylpiperazine (BZP) is synthetic stimulant. It was legal and openly sold in New Zealand before October 1, 2008. Two cases of life-threatening toxicity associated with BZP use are reported in detail in this article. Case one describes an adult female
Ellen I Dixon et al.
International journal of developmental neuroscience : the official journal of the International Society for Developmental Neuroscience, 73, 32-40 (2018-12-28)
From 30 days after birth until the completion of the study, male and female rats were caged in same-sexed twos or threes either with (enriched cages, EC) or without several objects for them to explore (standard cages, SC). From 41
The crystal structure of the complex of the anticancer prodrug 7-ethyl-10-[4-(1-piperidino)-1-piperidino]-carbonyloxycamptothecin (CPT-11) with Torpedo californica acetylcholinesterase provides a molecular explanation for its cholinergic action.
Harel M, et al.
Molecular Pharmaceutics, 67(6), 1874-1881 (2005)
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