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Merck

KCND2

potassium voltage-gated channel, Shal-related subfamily, member 2

Sinonimi:
KV4.2, RK5
Specie:
ID UniProtKB:
ID gene:
  • Human(3751) Summary: Voltage-gated potassium (Kv) channels represent the most complex class of voltage-gated ion channels from both functional and structural standpoints. Their diverse functions include regulating neurotransmitter release, heart rate, insulin secretion, neuronal excitability, epithelial electrolyte transport, smooth muscle contraction, and cell volume. Four sequence-related potassium channel genes - shaker, shaw, shab, and shal - have been identified in Drosophila, and each has been shown to have human homolog(s). This gene encodes a member of the potassium channel, voltage-gated, shal-related subfamily, members of which form voltage-activated A-type potassium ion channels and are prominent in the repolarization phase of the action potential. This member mediates a rapidly inactivating, A-type outward potassium current which is not under the control of the N terminus as it is in Shaker channels. [provided by RefSeq, Jul 2008]
  • Mouse(16508) potassium voltage-gated channel, Shal-related family, member 2
  • Rat(65180) potassium voltage-gated channel, Shal-related subfamily, member 2
  • sheep(101122690) potassium voltage-gated channel, Shal-related subfamily, member 2
  • Domestic Rabbit(100008841) potassium voltage-gated channel, Shal-related subfamily, member 2
  • domestic guinea pig(100720728) potassium voltage-gated channel, Shal-related subfamily, member 2
  • naked mole-rat(101712898) potassium voltage-gated channel, Shal-related subfamily, member 2
  • chicken(374143) potassium voltage-gated channel, Shal-related subfamily, member 2
  • Zebrafish(570188) potassium voltage-gated channel, Shal-related subfamily, member 2
  • dog(491424) potassium voltage-gated channel, Shal-related subfamily, member 2
  • domestic cat(101093262) potassium voltage-gated channel, Shal-related subfamily, member 2
  • cow(540416) potassium voltage-gated channel, Shal-related subfamily, member 2

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Antibodies

N° Catalogo
Descrizione
Reattività con
Applicazione
Anti-KCND2 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Reattività con
human
Applicazione
immunohistochemistry
Anti-Potassium Channel Kv4.2 Antibody, Chemicon®, from rabbit,
Reattività con
rat
Applicazione
western blot
Anti-KCND2 antibody produced in rabbit, affinity isolated antibody,
Reattività con
bovine, horse, human, mouse, pig, rabbit, rat
Applicazione
western blot
Anti-Potassium Channel Kv4.2 (Shal1; RK5; Kcnd2) antibody produced in rabbit, affinity isolated antibody, lyophilized powder,
Reattività con
human, rat
Applicazione
western blot

Small Molecule - Blocker

N° Catalogo
Descrizione
Specie
Guanidina, for molecular biology, ≥99%,
Specie
human
Guanidina, ≥98%,
Specie
human
Guanidina, organic base and chaeotropic agent, ≥99% (titration),
Specie
human
Guanidina, ,
Specie
human
Guanidina, Colorless liquid, 7.8 - 8.3 M, pH- 4.5 - 5.5,
Specie
human

esiRNA

N° Catalogo
Descrizione
Specie
MISSION® esiRNA, targeting mouse Kcnd2,
Specie
mouse
MISSION® esiRNA, targeting human KCND2,
Specie
human