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Merck

GRIK2

glutamate receptor, ionotropic, kainate 2

Sinonimi:
EAA4, GLR6, GLUK6, GLUR6, GluK2, MRT6
Specie:
ID UniProtKB:
ID gene:
  • Human(2898) Summary: Glutamate receptors are the predominant excitatory neurotransmitter receptors in the mammalian brain and are activated in a variety of normal neurophysiologic processes. This gene product belongs to the kainate family of glutamate receptors, which are composed of four subunits and function as ligand-activated ion channels. The subunit encoded by this gene is subject to RNA editing at multiple sites within the first and second transmembrane domains, which is thought to alter the structure and function of the receptor complex. Alternatively spliced transcript variants encoding different isoforms have also been described for this gene. Mutations in this gene have been associated with autosomal recessive mental retardation. [provided by RefSeq, Jul 2008]
  • Mouse(14806) glutamate receptor, ionotropic, kainate 2 (beta 2)
  • Rat(54257) glutamate receptor, ionotropic, kainate 2
  • chicken(428628) glutamate receptor, ionotropic, kainate 2
  • dog(481938) glutamate receptor, ionotropic, kainate 2
  • Thale Cress(836176) geminivirus rep interacting kinase 2
  • Zebrafish(556013) glutamate receptor, ionotropic, kainate 2
  • cow(615226) glutamate receptor, ionotropic, kainate 2
  • naked mole-rat(101697577) glutamate receptor, ionotropic, kainate 2
  • domestic guinea pig(100733104) glutamate receptor, ionotropic, kainate 2
  • sheep(101122701) glutamate receptor, ionotropic, kainate 2

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Small Molecule - Agonist

N° Catalogo
Descrizione
Specie
L-Glutamic acid hydrochloride, ,
Specie
human
(±)-AMPA, solid,
Specie
rat
(S)-AMPA, ≥97%,
Specie
mouse, human, rat
Kainic acid monohydrate, ≥99% (TLC),
Specie
human, mouse, rat
(Aminomethyl)phosphonic acid, 99%,
Specie
rat, human

Small Molecule - Antagonist

N° Catalogo
Descrizione
Specie
CNQX, ≥98% (HPLC), solid,
Specie
rat
NBQX disodium salt hydrate, ≥98% (HPLC),
Specie
human
DNQX, ≥98% (TLC),
Specie
mouse, rat, human
(±)-AMPA, solid,
Specie
rat
(S)-AMPA, ≥97%,
Specie
mouse, human, rat

Antibodies

N° Catalogo
Descrizione
Reattività con
Applicazione
Anti-GluR6/7 Antibody, clone NL9, rabbit monoclonal, culture supernatant, clone NL904, Upstate®,
Reattività con
human, mouse, rat
Applicazione
immunoprecipitation (IP)
western blot
Anti-GRIK2 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Reattività con
human, mouse, rat
Applicazione
immunohistochemistry
western blot
Anti-GRIK2 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Reattività con
human
Applicazione
immunohistochemistry
Anti-GRIK2 antibody produced in rabbit, affinity isolated antibody,
Reattività con
bovine, dog, guinea pig, horse, human, mouse, rabbit, rat
Applicazione
western blot
Anti-GRIK2 (AB2) antibody produced in rabbit, IgG fraction of antiserum,
Reattività con
bovine, dog, guinea pig, horse, human, mouse, rabbit, rat
Applicazione
immunohistochemistry
western blot

Small Molecule - Mixed Agonist/Antagonist

N° Catalogo
Descrizione
Specie
(±)-AMPA, solid,
Specie
rat
Kainic acid monohydrate, ≥99% (TLC),
Specie
human, mouse, rat
Acido L-glutammico, ReagentPlus®, ≥99% (HPLC),
Specie
rat, human
Acido L-glutammico, from non-animal source, meets EP testing specifications, suitable for cell culture, 98.5-100.5%,
Specie
rat, human
Acido L-glutammico, BioUltra, ≥99.5% (NT),
Specie
rat, human

esiRNA

N° Catalogo
Descrizione
Specie
MISSION® esiRNA, targeting human GRIK2 (1),
Specie
human
MISSION® esiRNA, targeting human GRIK2 (2),
Specie
human