Teratogenesis, carcinogenesis, and mutagenesis, 9(6), 349-357 (1989-01-01)
Tetrachloroethane (TTCE), pentachloroethane (PCE), and hexachloroethane (HCE) were tested in diploid strain (D7) of the yeast Saccharomyces cerevisiae in suspension test with and without mammalian metabolic activation (S9). TTCE, PCE, and HCE gave positive results on cells harvested from logarithmic
Fundamental and applied toxicology : official journal of the Society of Toxicology, 31(2), 229-242 (1996-06-01)
A physiologically based toxicokinetic model was developed to describe dermal absorption of waterborne organic chemicals by fish. The skin was modeled as a discrete compartment into which compounds diffuse as a function of chemical permeability and the concentration gradient. The
A heme model system for the reduction of substrates by microsomal cytochrome P 450.
D Mansuy et al.
Biochemical and biophysical research communications, 104(4), 1651-1657 (1982-02-26)
Pentachloroethane.
IARC monographs on the evaluation of the carcinogenic risk of chemicals to humans, 41, 99-111 (1986-01-01)
Research communications in chemical pathology and pharmacology, 63(1), 81-91 (1989-01-01)
The in vivo covalent binding of 14C-pentachloroethane to DNA, RNA and proteins of rats and mouse organs was detected 22 hr after i.p. injection. The covalent binding index, calculated on the liver labeling was comparable to those of compounds considered
Notre équipe de scientifiques dispose d'une expérience dans tous les secteurs de la recherche, notamment en sciences de la vie, science des matériaux, synthèse chimique, chromatographie, analyse et dans de nombreux autres domaines..