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U2625

Sigma-Aldrich

Uric acid

≥99%, crystalline

Synonyme(s) :

2,6,8-Trihydroxypurine

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25 G
93.00 CHF
100 G
301.00 CHF
1 KG
2 040.00 CHF

93.00 CHF


Date d'expédition estimée le30 mai 2025


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25 G
93.00 CHF
100 G
301.00 CHF
1 KG
2 040.00 CHF

About This Item

Formule empirique (notation de Hill) :
C5H4N4O3
Numéro CAS:
Poids moléculaire :
168.11
Beilstein:
156158
Numéro CE :
Numéro MDL:
Code UNSPSC :
12352005
ID de substance PubChem :
Nomenclature NACRES :
NA.55

93.00 CHF


Date d'expédition estimée le30 mai 2025


Devis pour commande en gros

Essai

≥99%

Forme

crystalline

Pf

>300 °C (lit.)

Chaîne SMILES 

O=C1NC(=O)C2=C(N1)NC(=O)N2

InChI

1S/C5H4N4O3/c10-3-1-2(7-4(11)6-1)8-5(12)9-3/h(H4,6,7,8,9,10,11,12)

Clé InChI

LEHOTFFKMJEONL-UHFFFAOYSA-N

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Application

Uric acid has been used:
  • in inducing hyperuricemia in mice[1]
  • as a component of digestion fluid for the simulation of in vitro human digestion model[2]
  • in selectivity test of the glucose sensor in sweat-based diabetes monitoring [3]

Actions biochimiques/physiologiques

Uric acid is an insoluble catabolite produced by adenine and guanine metabolism. Accumulation of uric acid leads to gout, hyperuricemia, arthritis and renal failure.[4] Elevated uric acid levels contributes to hypertension and pathogenesis of cardiovascular disease.[5][6] Low uric acid levels associated with Parkinson′s disease and multiple sclerosis, may elicit protective functionality.[6] High levels of uric acid in patients with chronic obstructive pulmonary disease (COPD) may serve as potential marker for diagnosis.[7]

Code de la classe de stockage

11 - Combustible Solids

Classe de danger pour l'eau (WGK)

WGK 2

Point d'éclair (°F)

Not applicable

Point d'éclair (°C)

Not applicable

Équipement de protection individuelle

Eyeshields, Gloves, type N95 (US)


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Les clients ont également consulté

Uric acid in plants and microorganisms: Biological applications and genetics-A review
Hafez RM, et al.
Journal of Advanced Research, 8(5), 475-486 (2017)
A graphene-based electrochemical device with thermoresponsive microneedles for diabetes monitoring and therapy
Lee H, et al.
Nature Nanotechnology, 11(6), 566-566 (2016)
Serum uric acid: a risk factor and a target for treatment?
Feig DI, et al.
Journal of the American Society of Nephrology, 17(4), S69-S73 (2006)
Reduction of Serum Uric Acid Associated with Attenuation of Renal Injury, Inflammation and Macrophages M1/M2 Ratio in Hyperuricemic Mice Model
HARYONO A, et al.
Kobe J. Med. Sci., 64(3), E107-E114 (2018)
Uric acid, hyperuricemia and vascular diseases
Jin M, et al.
Frontiers in Bioscience, 17, 656-656 (2012)

Articles

Uric acid present in animal sera impacts serum-supplemented classical cell culture systems, influencing cell culture performance.

Questions

1–2 of 2 Questions  
  1. How can I determine the shelf life / expiration / retest date of this product?

    1 answer
    1. If this product has an expiration or retest date, it will be shown on the Certificate of Analysis (COA, CofA). If there is no retest or expiration date listed on the product's COA, we do not have suitable stability data to determine a shelf life. For these products, the only date on the COA will be the release date; a retest, expiration, or use-by-date will not be displayed.
      For all products, we recommend handling per defined conditions as printed in our product literature and website product descriptions. We recommend that products should be routinely inspected by customers to ensure they perform as expected.
      For products without retest or expiration dates, our standard warranty of 1 year from the date of shipment is applicable.
      For more information, please refer to the Product Dating Information document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/449/386/product-dating-information-mk.pdf

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  2. How is shipping temperature determined? And how is it related to the product storage temperature?

    1 answer
    1. Products may be shipped at a different temperature than the recommended long-term storage temperature. If the product quality is sensitive to short-term exposure to conditions other than the recommended long-term storage, it will be shipped on wet or dry-ice. If the product quality is NOT affected by short-term exposure to conditions other than the recommended long-term storage, it will be shipped at ambient temperature. As shipping routes are configured for minimum transit times, shipping at ambient temperature helps control shipping costs for our customers. For more information, please refer to the Storage and Transport Conditions document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/316/622/storage-transport-conditions-mk.pdf

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