H7890

L-Homoserine lactone hydrochloride

suitable for ligand binding assays

• Formule empirique (notation de Hill): C₄H₇NO₂ · HCl
• Numéro CAS: 2185-02-6
• Poids moléculaire : 137.56
• Numéro MDL: MFCD00058172
• Code UNSPSC : 12352209
• ID de substance PubChem : 24895811
• Nomenclature NACRES : NA.26

Propriétés

• product name: L-Homoserine lactone hydrochloride,
• Forme: powder
• Technique(s): ligand binding assay: suitable
• Couleur: white
• Température de stockage: −20°C
• Chaîne SMILES: Cl.N[C@H]1CCOC1=O
• InChI: 1S/C4H7NO2.ClH/c5-3-1-2-7-4(3)6;/h3H,1-2,5H2;1H/t3-;/m0./s1
• Clé InChI: XBKCXPRYTLOQKS-DFWYDOINSA-N

Description

Description générale

L-Homoserine lactone (HSL), also called acyl-HSL, comprises a homoserine lactone ring and a fatty acyl side. The levels of acyl-HSL in bacteria is dictated by the availability of the substrates and acyl-homoserine lactones synthase.

Application

L-Homoserine lactone hydrochloride has been used as an inhibitor for arterial smooth muscle contraction.

Actions biochimiques/physiologiques

L-Homoserine lactone inhibition reduces virulence factors and halts inflammation and tissue damage. In Pseudomonas aeruginosa it controls virulence factor production and biofilm formation. In Agrobacterium tumefaciens, it is essential for conjugal transfer.

Acylated L-Homoserine lactone(s) are used to study bacterial quorum-sensing signaling mechanisms.

Informations sur la sécurité

• Code de la classe de stockage: 11 - Combustible Solids
• Classe de danger pour l'eau (WGK): WGK 3
• Point d'éclair (°F): Not applicable
• Point d'éclair (°C): Not applicable
• Équipement de protection individuelle: Eyeshields, Gloves, type N95 (US)