D7750

2′-Deoxycytidine 5′-monophosphate

Sigma Grade, ≥95.0%

• Synonyme(s) : Deoxycytidylic acid, dCMP
• Formule empirique (notation de Hill) : C₉H₁₄N₃O₇P
• Numéro CAS: 1032-65-1
• Poids moléculaire : 307.20
• Beilstein: 41062
• Numéro CE : 213-849-9
• Numéro MDL: MFCD00006546
• Code UNSPSC : 41106305
• ID de substance PubChem : 24894158
• Nomenclature NACRES : NA.51

Propriétés

• Source biologique: synthetic
• Qualité: Sigma Grade
• Essai: ≥95.0%
• Forme: powder
• Solubilité: 1 M NH₄OH: 50 mg/mL, clear, colorless
• Température de stockage: −20°C
• Chaîne SMILES: NC1=NC(=O)N(C=C1)[C@H]2C[C@H](O)[C@@H](COP(O)(O)=O)O2
• InChI: 1S/C9H14N3O7P/c10-7-1-2-12(9(14)11-7)8-3-5(13)6(19-8)4-18-20(15,16)17/h1-2,5-6,8,13H,3-4H2,(H2,10,11,14)(H2,15,16,17)/t5-,6+,8+/m0/s1
• Clé InChI: NCMVOABPESMRCP-SHYZEUOFSA-N

Description

Description générale

2′-Deoxycytidine 5′-monophosphate is a deoxynucleotide building block via which DNA is made. It consists of a 2′-deoxy-β-D-ribofuranose, linked through an N-β-D-glycosidic linkage to a heterocycle nitrogen cytosine. It is phosphorylated at carbon C-5′.[1]

Application

2′-Deoxycytidine 5′-monophosphate (dCMP) is used as a substrate of uridine monophosphate (UMP)/cytidine monophosphate (CMP) kinase (EC 2.7.4.4) to form dCDP which upon phosphorylation to dCTP supports DNA biosynthesis.

2′-Deoxycytidine 5′-monophosphate has been used in Raman spectroscopic studies to determine its Raman total half bandwidths.[2]

Informations sur la sécurité

• Code de la classe de stockage: 11 - Combustible Solids
• Classe de danger pour l'eau (WGK): WGK 3
• Point d'éclair (°F): Not applicable
• Point d'éclair (°C): Not applicable
• Équipement de protection individuelle: Eyeshields, Gloves, type N95 (US)