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Principaux documents

B7929

Sigma-Aldrich

Anti-Bim antibody produced in rabbit

affinity isolated antibody, buffered aqueous solution

Synonyme(s) :

Anti-BOD

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About This Item

Numéro MDL:
MFCD02095895
Code UNSPSC :
12352203

Source biologique

rabbit

Conjugué

unconjugated

Forme d'anticorps

affinity isolated antibody

Type de produit anticorps

primary antibodies

Clone

polyclonal

Forme

buffered aqueous solution

Poids mol.

antigen 23 kDa

Espèces réactives

human, rat, mouse

Technique(s)

immunohistochemistry: 20 μg/mL using human skin cancer cells
microarray: suitable
western blot: 1 μg/mL using A549 or K562 whole cell lysates

Numéro d'accès UniProt

O43521

Conditions d'expédition

dry ice

Température de stockage

−20°C

Modification post-traductionnelle de la cible

unmodified

Informations sur le gène

human ... BCL2L11(10018)
mouse ... Bcl2l11(12125)
rat ... Bcl2l11(64547)

Immunogène

synthetic peptide corresponding to amino acids 22-40 of human Bim (BOD). This sequence is identical in mouse and contains only one amino acid substitution in rat.

Forme physique

Solution in phosphate buffered saline containing 0.02% sodium azide

Clause de non-responsabilité

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Code de la classe de stockage

12 - Non Combustible Liquids

Classe de danger pour l'eau (WGK)

nwg

Point d'éclair (°F)

Not applicable

Point d'éclair (°C)

Not applicable

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Certificats d'analyse (COA)

Lot/Batch Number
SLBT5339
SLBN0190V
071M1321
120M1983
070M1217

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Laura Elisa Buitrago-Molina et al.
Cellular and molecular gastroenterology and hepatology, 11(5), 1387-1404 (2021-01-24)
A coordinated stress and regenerative response is important after hepatocyte damage. Here, we investigate the phenotypes that result from genetic abrogation of individual components of the checkpoint kinase 2/transformation-related protein 53 (p53)/cyclin-dependent kinase inhibitor 1A (p21) pathway in a murine
Violeta Gómez-Vicente et al.
The European journal of neuroscience, 24(4), 981-990 (2006-08-26)
Apoptosis of photoreceptor cells in the early postnatal period is a normal feature of mammalian retinal development. The role of mitochondria and caspases in the process has been well established; however, the identification of key apoptotic mediators still remains elusive.
P Geserick et al.
Cell death & disease, 5, e1412-e1412 (2014-09-12)
Tumour progression and therapy resistance in squamous cell carcinoma of the skin (SCC) is strongly associated with resistance to intrinsic mitochondrial apoptosis. We thus investigated the role of various anti-apoptotic Bcl-2 proteins for apoptosis protection in SCC using the BH3
Nina Stojcheva et al.
Oncotarget, 7(11), 12937-12950 (2016-02-18)
Glioblastoma is the most aggressive brain tumor in adults with a median survival below 12 months in population-based studies. The main reason for tumor recurrence and progression is constitutive or acquired resistance to the standard of care of surgical resection
Aya Khamis et al.
Cancers, 14(20) (2022-10-28)
Treatment success of head and neck squamous cell carcinoma (HNSCC) is often hindered by cisplatin resistance. As inherent and acquired therapy resistance counteracts improvement in long-term survival, novel multi-targeting strategies triggering cancer cell apoptosis are urgently required. Here, we identify
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