B5438

Balsalazide disodium salt hydrate

• Synonyme(s) : 5-[4-(2-Carboxyethylcarbamoyl)phenylazo]salicylic acid disodium salt hydrate
• Formule empirique (notation de Hill) : C₁₇H₁₃N₃Na₂O₆ · xH₂O
• Numéro CAS: 213594-60-6
• Poids moléculaire : 401.28 (anhydrous basis)
• Numéro MDL: MFCD18632541
• Code UNSPSC : 12352100
• ID de substance PubChem : 329773261
• Nomenclature NACRES : NA.25

Propriétés

• Essai: ≥99% (HPLC)
• Forme: powder
• Température de stockage: 2-8°C
• Chaîne SMILES: O.[Na+].[Na+].Oc1ccc(cc1C([O-])=O)\N=N\c2ccc(cc2)C(=O)NCCC([O-])=O
• InChI: 1S/C17H15N3O6.2Na.H2O/c21-14-6-5-12(9-13(14)17(25)26)20-19-11-3-1-10(2-4-11)16(24)18-8-7-15(22)23;;;/h1-6,9,21H,7-8H2,(H,18,24)(H,22,23)(H,25,26);;;1H2/q;2*+1;/p-2/b20-19+;;;
• Clé InChI: ZZZXQZHSFPVNCR-HVARVCSCSA-L

Description

Actions biochimiques/physiologiques

Balsalazide has antioxidative and anti-inflammatory properties. It inhibits superoxide production and was found to scavenge hypochlorite radicals. Balsalazide was shown to inhibit lipid peroxidation in rat intestinal mucosa. It was also shown to inhibit azoxymethane-induced colon carcinogenesis. In vivo, basalazide is cleaved through azoreduction to produce 4-aminobenzoyl-β-alanine, an inert carrier moiety, and 5-aminosalicylic acid (5-ASA).

Informations sur la sécurité

• Code de la classe de stockage: 11 - Combustible Solids
• Classe de danger pour l'eau (WGK): nwg
• Point d'éclair (°F): Not applicable
• Point d'éclair (°C): Not applicable