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Principaux documents

32856

Sigma-Aldrich

May-Grünwald solution

according to May-Grünwald

Synonyme(s) :

Eosin – methylene blue solution, Eosin methylene blue according to May-Grünwald

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About This Item

Numéro CE :
Numéro MDL:
Code UNSPSC :
12171500
ID de substance PubChem :

Qualité

according to May-Grünwald

Adéquation

passes test for UV spectrum

Chaîne SMILES 

[K+].COC(=O)c1ccccc1C2=C3C=C(Br)C(=O)C(Br)=C3Oc4c(Br)c([O-])c(Br)cc24

InChI

1S/C21H10Br4O5.K/c1-29-21(28)9-5-3-2-4-8(9)14-10-6-12(22)17(26)15(24)19(10)30-20-11(14)7-13(23)18(27)16(20)25;/h2-7,26H,1H3;/q;+1/p-1

Clé InChI

NXBZXYJXNIFCRJ-UHFFFAOYSA-M

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Description générale

May-Grünwald-Giemsa (MGG) stain is a Romanowsky-type, polychromatic stain as those of Giemsa, Leishman and Wright. It is used as reference stain in haematology. It is also used as routine stain in diagnostic cytopathology for the study of air-dried preparations (centrifuged body fluids, lymph node imprints, and fine needle aspirations).

Application

May-Grünwald and Giemsa stain was used for staining polymorphonuclear cells, monocytes and lymphocytes, for differential leukocyte counts, during hematological analysis, in an experimental study conducted to study immune responses in the pathology of acute magnesium deficiency in rats. It was also used to stain cells from bronchoalveolar lavage (BAL) fluid, in an experimental investigation, done to study the role of Fas ligand in murine silicosis.

Pictogrammes

FlameSkull and crossbonesHealth hazard

Mention d'avertissement

Danger

Classification des risques

Acute Tox. 3 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Flam. Liq. 2 - STOT SE 1

Organes cibles

Eyes

Code de la classe de stockage

3 - Flammable liquids

Classe de danger pour l'eau (WGK)

WGK 2

Point d'éclair (°F)

53.6 °F

Point d'éclair (°C)

12 °C

Équipement de protection individuelle

Eyeshields, Faceshields, Gloves


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Eric Piaton et al.
Annales de pathologie, 35(4), 294-305 (2015-07-21)
May-Grünwald-Giemsa (MGG) stain is a Romanowsky-type, polychromatic stain as those of Giemsa, Leishman and Wright. Apart being the reference method of haematology, it has become a routine stain of diagnostic cytopathology for the study of air-dried preparations (lymph node imprints
Fas ligand triggers pulmonary silicosis.
Borges VM
The Journal of Experimental Medicine, 194 (2), 155-164 (2001)
Inflammatory response following acute magnesium deficiency in the rat.
Malpuech BC
Biochim. Biophys. Acta Gen. Subj., 1501 (2), 91-98 (2000)
Young-Whan Choi et al.
Journal of ethnopharmacology, 178, 17-24 (2015-12-18)
The giant butterbur Petasites japonicus is used to treat asthma and allergic diseases in traditional Korean, Japanese, and Chinese medicine. To elucidate the anti-allergic effect of Petasites genus, we studied effects of several compounds from Petasites japonicus leaves and found
Mi-Jeong Kim et al.
European journal of pharmacology, 852, 25-33 (2019-02-25)
The effects of candesartan and irbesartan, antagonists of the type I angiotensin II receptor, were investigated on allergic asthma. The antigen-induced degranulation was measured by evaluating β-hexosaminidase activity in vitro. Additionally, a murine ovalbumin-induced allergic asthma model was used to

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